The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation. Mutation DNA Sequence None 5'..A TG GAG G T ATTA TA G.. 3' A 5' ..A TG GGCGAGATAT TATA G.. 3' В 5' ..A TGGGCGAG GTA CTATA G.. 3' C 5'..A TGGCCGAGGTATTATA G.. 3' The region without a mutation s transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- -C Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein
The following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation. Mutation DNA Sequence None 5'..A TG GAG G T ATTA TA G.. 3' A 5' ..A TG GGCGAGATAT TATA G.. 3' В 5' ..A TGGGCGAG GTA CTATA G.. 3' C 5'..A TGGCCGAGGTATTATA G.. 3' The region without a mutation s transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- -C Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Transcribed Image Text:### DNA Sequence Analysis
The following is the DNA sequence of the entire protein-coding region for a small gene in a eukaryote. Displayed below are the coding strands. The first row is the original sequence without mutations. Subsequent rows represent a single mutation.
#### DNA Sequences
- **None**
5’ …ATGGGCGAGGATTATTATAG… 3’
- **Mutation A**
5’ …ATGGGACAGGATTATTATAG… 3’
- **Mutation B**
5’ …ATGGGCGAGGATTACTATAG… 3’
- **Mutation C**
5’ …ATGGGCGAGGATTATTATAG… 3’
#### Protein Translation
Translate the region without a mutation. Provide the protein translated from this DNA strand using single-letter amino acid abbreviations with no spaces.
N-______-C
#### Mutation Analysis
Identify the molecular basis and the effect of each mutation on the protein.
| Mutation | Molecular Basis | Effect on Protein |
|--------------|-----------------------|-------------------------|
| A | | |
| B | | |
| C | | |
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