How would the following affect BOTH transcription and translation of a particular multi- exon gene in a eukaryotic cell (for each address both transcription and translation of a particular multi-exan gene; also treat each independently): 1. A mutation abolishing kinase activity in TFIIH a. b. A mutation abolishing mRNA binding in the snRNP U1 С. A mutation in aminoacyl tRNA synthetase for isoleucine such that it can't bind ATP (assume there is an isoleucine in the code)

Q: 67 RNA interference was first discovered in Drosophila melanogaster. Yes or no 68 Which of the…

A:

Q: What would be the direct consequence to a cell of loss-of-function of Elongation Factor-Tu (EF-Tu)?…

A: EF-Tu is a highly conserved elongation factor in prokaryotes. It catalyzes the binding of tRNA…

Q: Genes in both prokaryotes and eukaryotes are regulated by activators and repressors.a. Compare and…

A: Gene regulation refers to the mechanisms that are responsible for the repression or induction of…

Q: Consider the Rho-dependent terminator sequence 5’CCCAGCCCGCCUAAUGAGCGGCCUUUUUUUU-3’. What affect…

A: The mutation is the change in the nucleotide sequence of the DNA. The point mutation is the mutation…

Q: Genetic expression involves transcription and translation. Match the structure or molecule to the…

A: Nucleic acids are a type of macromolecules present in the cell.

Q: Discuss how the expression of a protein can be regulated post transcription in eukaryotic cells…

A: The eukaryotic cell after transcription called the primary transcript is not considered as messenger…

Q: synaptic knobs of a nueron have what function? a. they release neurotransmitter into the synaptic…

A: The nervous system is the specialized system that controls the sensory and motor activity in the…

Q: What are the functional consequences of this deletion for lilP mRNA transcription and translation?…

A: Introduction :- A deletion mutation is a type of genetic mutation that involves the loss of one or…

Q: . One mechanism by which antisense RNAs act as negative regulators of gene expression is by base…

A: The antisense RNA is a type of single-stranded RNA molecule that binds to the complementary…

Q: sRNA acts as a marker, flagging the inhibitory protein for ubiquitination and allowing translation…

A: Proteins are synthesized by the process of translation and are modified after post-translational…

Q: 3). Consider the four mutations (i-iv) described below: i. One of the mutations causing cystic…

A: A mutation is a permanent change in the DNA sequence of an organism's genome. Mutations can occur…

Q: The following RNA sequence represents a small messenger which can be translated in a prokaryotic…

A: The first step in translating an RNA sequence into a protein is to divide the sequence into codons,…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

A: Cancer  Cancer if a kind of disorder which caused by several means like drug, radiation, malfunction…

Q: Would the cell likely experience an issue due to the incorrect function of the protein produced by…

A: DNA ( deoxyribonucleic and) is a genetic material in most of the organism that appear as two…

Q: Comparison of different tissues shows that the ITY gene produces a 900 nt mature mRNA and a 190…

A: Alternative splicing is the mechanism that produces multiple mature mRNAs from a single primary…

Q: ATM is a kinase that phosphorylates histone H2AX in response to double-stranded DNA breaks. Which of…

A: ATM (Ataxia Telangiectasia Mutated) is a protein kinase that plays a critical role in the cellular…

Q: Give one example of a prokaryotic system of gene expression that is more complicated (during…

A: Gene expression refers to the process by which the information stored in a gene is used to…

Q: mRNA maturation in eukaryotes includes all of the following EXCEPT: A. Topoisomerase activity B.…

A: In eukaryotic cells, the primary transcript undergoes post transcriptional modification to form a…

Q: What region would provide cell type-specific expression of genes? region  What site would…

A: The mRNA is given in the figure. The mRNA undergoes the process of translation to produce protein.

Q: Consider a mutation in -10 BOX promoter consensus sequence (TATAAT) in the prokaryote recA gene…

A: TATTAT is called pribnow box in prokaryotes and is a promoter sequence that tells the Enzymes where…

Q: The IMD2 promoter contains three upstream transcription start sites (TSS) that are utilized under…

A: Inosine monophosphate dehydrogenase (IMD2) is a key enzyme in the purine biosynthesis pathway that…

Q: Consider a gene being transcribed at a constant rate k1 and being degraded with first  order…

A: The genetic information from protein synthesis is stored in DNA. This information is copied onto an…

Q: What conditions would we find on the gene of a prokaryote if there is low amounts of tryptophan…

A: Tryptophan is less common amino acid found in protein. They plays an important role in structural…

Q: What effect would inhibitors of histone deacetylases have upon transcription? Group of answer…

A: Introduction :  The protein histones is very alkaline. In eukaryotic cells, they are located in the…

Q: Sequential binding of RNA polymerase II-TFIIF complex, TFIIE, and TFIIH completes…

A: RNA Polymerase II is responsible for the transcription of messenger RNA with the help of DNA. For…

Q: Please study the diagram above on eukaryotic gene expression. In order to provide instructions for…

A: EXPLANATION : Noncoding DNA is also found within most of the eukaryotic genes. Such genes have a…

Q: You are a scientist studying drug resistance in cancer. You are particularly interested in ABCB1, a…

A: Cancer causes the uncontrolled growth of abnormal cells and dynamic altering in the genome. Common…

Q: principle function of 5 ons of eukaryotic mRNA IS: a. to ensure that all nucleotides are…

A: Transcription is process in which DNA equence is copied to make RNA. Its the first step of gene…

Q: G3A (G at position 3 was changed to A) G9A Deletion of TCA at position 18-20 C22A T31A, A32T double…

A: The Mendelian gene is a basic unit of the heredity and the molecular gene is a sequence of…

Q: The chart below is a position specific scoring matrix (PSSM, a logarithmic transformed matrix) for a…

A: Hi, Thanks For Your Question.  Q2. Answer : The Maximum Score That A Sequence Can Have With This…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.