Define (whether post-transcriptional, post-translational, transcription) and describe the regulation of the Ferretin mRNA in the diagram below. ### Regulation of Ferritin Translation by Iron Concentration#### A. Low Iron ConcentrationAt low iron concentrations, the iron regulatory protein (IRP) is active. It binds to the iron-responsive element (IRE) on the mRNA's 5' untranslated region, preventing translation of the ferritin-coding region. This inhibition ensures that ferritin, an iron-storage protein, is not produced when iron levels are insufficient.- **Diagram Explanation:** - The mRNA is represented as a linear strand, with the 5' end on the left and the 3' end on the right. - The IRE is depicted as a loop structure where the active IRP (shown in purple) is bound. - Downstream is the ferritin-coding region, marked in red, which is not translated in this state.#### B. High Iron ConcentrationWith high iron concentrations, iron ions bind to the IRP, rendering it inactive and unable to bind to the IRE. This enables the ribosome (depicted in blue) to access the mRNA and initiate translation of the ferritin-coding region into the ferritin protein.- **Diagram Explanation:** - The mRNA maintains the same orientation as in panel A. - Inactive IRP, with iron shown in brown, is detached from the IRE. - The ribosome is positioned on the mRNA, initiating translation of the ferritin-coding region, producing ferritin. - Ferritin emerges from the ribosome as a growing peptide chain.This mechanism showcases the cell's ability to regulate protein synthesis based on available iron, ensuring efficient iron storage and homeostasis.

Name: Define (whether post-transcriptional, post-translational, transcriptio
Uploaded: 2024-03-20T06:42:41.000Z
Channel: Bartleby
Description: Define (whether post-transcriptional, post-translational, transcription) and describe the regulation of the Ferretin mRNA in the diagram below. ### Regulation of Ferritin Translation by Iron Concentration#### A. Low Iron ConcentrationAt low iron conc