The complete absence of one or more teeth (tooth agenesis) is a common trait in humans-indeed, more than 20% of humans lack one or more of their third molars. However, more severe absence of teeth, defined as missing six or more teeth, is less common and frequently an inherited condition. L. Lammi and colleagues examined tooth agenesis in the Finnish family shown in the pedigree below (L. Lammi, American Journal of Human Genetics 74:1043-1050. 2004). Which of the following modes of inheritance best fits the pattern observed in the pedigree? Note that the phenotypes in generation 1 are not known. 2. 8. 7 8 IV a. Y-linked Ob. X-linked dominant O C. X-linked recessive O d. Autosomal recessive e. Autosomal dominant

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