After hundreds or even thousands of generations, both alleles are still common in those of African ancestry. How would you explain this?

Q: What is the cause of Wolf-Hirschhorn and make sure to explain specifically why the karyotype of your…

A: Wolf-Hirschhorn syndrome (WHS) is a genetic disorder that affects many parts of the body. The major…

Q: Huntington's disease is a very rare, debilitating disease that affects approximately 1 in 10,000…

A: Autosomal genetic disorder is controlled by autosomes and X-linked genetic disorder is controlled by…

Q: Inborn errors of immunity (IEls) are a heterogeneous group of disorders due to genetic defects in…

A: Option 4 is correct.

Q: What phenotype is expressed from the genetic trait hemophilia?

A: The genetic trait hemophilia is an inheritable trait that exhibits the X-linked recessive…

Q: If it was determined that APO E4 interacted epistatically with one other gene, which form of…

A: A neurodegenerative condition known as Alzheimer's disease affects the brain and causes memory loss…

Q: A family with a history of a genetic disorder were analyzed with a dot blot using a probe for both…

A:

Q: The most common CF mutation is AF508; it accounts for approximate 70% of all mutant CFTR alleles…

A: Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive…

Q: population in Africa is mozygous individuals carrying the Val-6 mutation die from sickle cel emia…

A: Sickle Cell anaemia is a genetic disease that results from a point mutation that results in the…

Q: Junctional epidermolysis bullosa (JEB) is a severe skin disorder that results in blisters over the…

A: Junctional epidermolysis bullosa is type of skin disorder in which blisters develop on the skin of…

Q: Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a…

A: According to Hardy Weinberg`s equilibrium p2 + q2 +2pq =1 and p+q=1 p = frequency of the dominant…

Q: In mice, the autosomal locus coding for the β-globinchain of hemoglobin is 1 m.u. from the albino…

A: Since you have posted a question with multiple sub-parts, we are answering only first one for you.To…

Q: α-thalassemia is another blood disorder in which abnormal hemoglobin molecules are formed, leading…

A: A )    Hemoglobin Wayne is an alpha chain variation which shows itself as two minor hemoglobin (Hb)…

Q: For the following question, please explain in as much detail as possible. Below is a human pedigree…

A: A pedigree analysis plays an important role in determining the presence and absence of the diseased…

Q: ckle-cell anemia is an interesting genetic disease. Normal homozygous individials (SS) have normal…

A:

Q: Please discuss the following three scenarios (A, B and C) and their product(s)/outcome due to the…

A: The scenarios and their outcomes due to the single base mutation on Allele 2: Scenario A: The…

Q: MDF57 is a 110kDa DNA binding protein which has some functional roles in the development of…

A: Mutation is any change in the genetic setup of the cell such as change in the sequence, structure or…

Q: Why Recessive CF disease alleles either produce no CFTR or produce nonfunctional or less functional…

A: Cystic fibrosis (CF) is a classical example of recessive disease. It is a disease that is inherited.

Q: Define a Point mutation and give an example. What is sickle cell anemia and what causes it. What…

A: Mutation refers to the phenomena in which the structure of a gene or DNA sequence changes, resulting…

Q: The gene known to be mutated in cases of Agammaglobulinemia 2 (which is inherited in an autosomal…

A: A person with agammaglobulinemia has extremely low levels of the immune system's defense proteins,…

Q: The inheritance of one or more mutated genes can result in a genetic disease. Some genetic diseases…

A: Inheritance refers to the passing on of traits, characteristics or genetic information from parents…

Q: Anastasia was the youngest daughter of Czar Nicholas II of Russia. She had no known children, and…

A: Haemophilia is a sex-linked recessive disorder. The abnormal gene responsible for haemophilia is…

Q: The gene known to be mutated in cases of Agammaglobulinemia 2 (which is inherited in an autosomal…

A: A person with agammaglobulinemia has extremely low levels of the immune system's defense proteins,…

Q: Given that this mutated allele will cause disease and death in individuals, what would you predict…

A: Sickel cell anemia is an autosomal recessive genetic disorder that affects the shape of red blood…

Q: Two different variants (alleles) of ß-globin are found in African populations that offer some…

A: Hardy Weinberg’s principle is the mathematical representation of population analysis which…

Q: You've been having trouble sleeping because of your obsession with understanding the Rh factor (+…

A: Red blood cells(RBCs) consist of different antigens on their surface. The presence of these antigens…

Q: Sarah and George have been married for 6 years. They had a daughter 5 years ago and her blood type…

A: There are mainly four blood types in the humans. A, B, AB, and O  are the blood types present in the…

Q: The allele for sickle anemia is found at higher frequencies in central Africa than in other parts of…

A: Sickle anemia is a disease caused by sickle cell shaped red blood cells and is caused by the…

Q: In a region of Africa, where malaria is prevalent, 40% of the population are found to have…

A: The objective of the question is to calculate the relative fitness of the S1S1 homozygotes in a…

Q: This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the…

A: Answer is given below.

Q: One particularly useful feature of the Hardy-Weinberg equation is that it allows us to estimate the…

A: Hardy-Weinberg equilibrium states that, in a population allele and genotypic frequencies will remain…

Q: How would present allele frequencies of the sickle cell allele change, if there was no heterozygote…

A: Sickle cell anemia/SCA is an inherited-hematological disorder that significantly affects the shape…

Q: Following figure is showing the DNA fingerprint analysis on the ônë locus öf å man with four…

A: DNA fingerprinting is a test which uses Dna of a person at generate its fragments.

Q: In humans the allele coding for normal metabolism of the amino acid phenylalanine (P) is dominant…

A: The alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for…

A: Given: Cystic fibrosis (CF) is an autosomal recessive trait. Normal allele =  F      CF mutant…

Q: For the cell line H9c2(2-1) which is a rat mycardium cell line, what disease was it derived from?

A: The cell lines are inherited from different sources and hence keep distinct properties.

Q: DNA sequencing of your own two β-globin genes (one from each of your two Chromosome 11s) reveals a…

A: I should be worried since presence of an abnormal beta globin chains may be an early indicator of…

Hematology

Hematology is the branch of biology. Hematology is the medical field that deals with the treatment of blood disorders and cancers, such as hemophilia, leukemia, lymphoma, and sickle-cell anemia. Hematologists and hematopathologists are medical professionals who specialize in illnesses of the blood and its components.