Huntington's disease is a very rare, debilitating disease that affects approximately 1 in 10,000 people. The disease is caused by a particular type of genetic mutation (large number of CAG repea n a gene called huntingtin (HTT). Designate the disease-causing allele HTTD and the non-disease- causing allele HTTN. We know that individuals with genotype HTTN will not develop Huntington's Disease, but people with either HTTP/HTTD or HTTN/HTTD will develop the disease. Which allele is dominant--HTTN or HTTD? Explain your reasoning thoroughly, using the correct definition of dominance
Huntington's disease is a very rare, debilitating disease that affects approximately 1 in 10,000 people. The disease is caused by a particular type of genetic mutation (large number of CAG repea n a gene called huntingtin (HTT). Designate the disease-causing allele HTTD and the non-disease- causing allele HTTN. We know that individuals with genotype HTTN will not develop Huntington's Disease, but people with either HTTP/HTTD or HTTN/HTTD will develop the disease. Which allele is dominant--HTTN or HTTD? Explain your reasoning thoroughly, using the correct definition of dominance
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...
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![Huntington's disease is a very rare, debilitating disease that affects approximately 1 in 10,000
people. The disease is caused by a particular type of genetic mutation (large number of CAG repeats)
in a gene called huntingtin (HTT). Designate the disease-causing allele HTTP and the non-disease-
causing allele HTTN. We know that individuals with genotype HTTN will not develop Huntington's
Disease, but people with either HTTD/HTTP or HTTN/HTTD will develop the disease.
Which allele is dominant--HTTN or HTTP? Explain your reasoning thoroughly, using the correct
definition of dominance.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F01fc8d1d-e5b2-4964-a413-6d324e9c2a61%2F04a14be7-1fe9-4486-8222-4eb7a31ed1c1%2F88exscg_processed.png&w=3840&q=75)
Transcribed Image Text:Huntington's disease is a very rare, debilitating disease that affects approximately 1 in 10,000
people. The disease is caused by a particular type of genetic mutation (large number of CAG repeats)
in a gene called huntingtin (HTT). Designate the disease-causing allele HTTP and the non-disease-
causing allele HTTN. We know that individuals with genotype HTTN will not develop Huntington's
Disease, but people with either HTTD/HTTP or HTTN/HTTD will develop the disease.
Which allele is dominant--HTTN or HTTP? Explain your reasoning thoroughly, using the correct
definition of dominance.
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