Please discuss the following threescenarios (A, B and C) and theirproduct(s)/outcome due to the single basemutation on Allele 2.(two sentences max for each scenario,please)AAllele 1MNMNMAllele 2MAMMAllele 1BMNMNMAllele 2MAMMAllele 1CMMMAllele 2MMM

The scenarios and their outcomes due to the single base mutation on Allele 2: Scenario A: The…

Answered: Please discuss the following three…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for a family that carries the mutant allele for cystic fibrosis. Note that carriers are not colored in to allow you to figure out their genotypes. Normal allele = F CF mutant allele = f What is the genotype of individual #13? A) ff B) FF C) Ff D) it is impossible to tell
Yellow Spotted Marker 1 Marker 2 Marker 3 Marker 4 Black K8 KB KE KB I. Marker 1 Marker 2 Marker3 Marker KB k III. 1 7 8. 10 11 12 Marker 1 Marker 2 Marker 3 Marker 4 KB. -KB Gene K controls fur color and it has three alleles: B, s, and y. The pedigree shows the genotypes of the individuals in the K gene and the haplotypes for the four molecular markers in the region of the gene. a) what is the relationship between the three alleles? Use the pedigree to support your answer and refer to individuals by their positioning in the pedigree b) based on the pedigree and the haplotype at the four markers, where is gene K located? Support your answer. c) A genetic map of the 4 markers studied is shown below: Marker 1 Marker 2 Marker 3 Marker 4 JU 5 cM 6 cM 12 cM What is the probability that an offspring of a cross between l-1 and I-2 would have the haplotype below? Show your work. 3 1 1 1 1
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(healthy) Tom and his wife Julie are both carriers for cystic fibrosis, an autosomal recessive disease. Draw a Punnett square and be sure to include the following information for f credit: 1. Place the parents alleles at the top and on the left side. 2. Write in the allele crosses inside the Punnett squares. 3. Write out the genotypes probabilities for an offspring. 4. Write out the phenotype probabilities for an offspring. E 5. What is the chance that Tom and Julie's first child will have cystic fibrosis?
Below is a pedigree showing transmission of a disease; affected individuals are indicated by solid circles or boxes. Represented below the pedigree are two nylon membranes; DNA samples from each individual in the pedigree were spotted in identical fashion on each membrane. Each individual's DNA appears directly below his or her position in the pedigree. Each membrane was hybridized with allele specific oligonucleotides that detect the two alternative alleles of a single SNP locus (ASO 1 and ASO 2). Positive hybridization is represented as a filled circle and lack of hybridization is represented as an open circle. I 11 III IV V ASO 1 ASO 2 To 1 2 3 4 5 6 a. What is the mode of transmission of this disease? 12 b. Which SNP allele (ASO1 or ASO2) is originally linked to the disease gene? c. Draw a diagram of the event that gave rise to the genotype of individual IV-5. d. Individual V-1 is an unborn fetus. If the SNP locus is 10 CM from the disease locus, what is the likelihood that he will…
QTL mapping and GWA (association) mapping are two different methods used to identify genes that affect complex traits. For each of the following statements, choosewhether it applies to QTL mapping, association mapping, or both.whether it applies to QTL mapping, association mapping, or both.
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Sickle cell anemia is a genetic disease most common in those of African ancestry that results from the mutation of a single basepair. This mutation results in a change to the hemoglobin protein. In this experiment, “S” will represent the normal allele and “s” thesickle allele. They are codominant alleles. Therefore, SS is normal, Ss is not fatal but mildly symptomatic, and ss is debilitating,painful, and often fatal. After hundreds or even thousands of generations, both alleles are still common in those of African ancestry. How would you explain this?
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Please discuss the following three scenarios (A, B and C) and their product(s)/outcome due to the single base mutation on Allele 2. (two sentences max for each scenario, please) A Allele 1 MNMNM Allele 2 MAMM Allele 1 B MNMNM Allele 2 MAMM Allele 1 C MMM Allele 2 MMM