1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected, whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease are homozygous for the "normal" allele a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children might they expect? b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will have i) be normal ii) have thalassaemia minor iii) have thalassaemia major?

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.