1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected, whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease are homozygous for the "normal" allele a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children might they expect? b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will have i) be normal ii) have thalassaemia minor iii) have thalassaemia major?
1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected, whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease are homozygous for the "normal" allele a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children might they expect? b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will have i) be normal ii) have thalassaemia minor iii) have thalassaemia major?
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...
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![1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a
single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected,
whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease
are homozygous for the "normal" allele
a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children
might they expect?
b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will
have
i) be normal
ii) have thalassaemia minor
iii) have thalassaemia major?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F76fff467-4f98-4fcc-94dc-c31edce733db%2F3b5cebbb-5f52-4bca-a7e8-51993421d83c%2Fhpo8h9b_processed.jpeg&w=3840&q=75)
Transcribed Image Text:1) Thalassaemia is a form of anaemia common in Mediterranean populations and resulting from a mutation to a
single gene. It occurs in two forms. Individuals with thalassaemia major are homozygous and badly affected,
whilst those with thalassaemia minor are heterozygous and only mildly affected. Individuals free of the disease
are homozygous for the "normal" allele
a) A man with thalassaemia minor marries a normal woman. With respect to thalassaemia, what types of children
might they expect?
b) Both father and mother in a particular family have thalassaemia minor. What is the chance that their baby will
have
i) be normal
ii) have thalassaemia minor
iii) have thalassaemia major?
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