Retinoblastoma (Rb) is a malignant tumor of the eye that manifests in early childhood. Predisposition to retinoblastoma is an autosomal dominant trait with incomplete penetrance. For a certain form of low penetrance retinoblastoma, only 30% of children born with a mutated Rb allele develop eye tumors. If a heterozygous person carrying this mutation has children with a partner carrying two wild-type alleles, what is the probability that their first child will be affected by retinoblastoma? (Give the answer as a percentage including the % sign e.g. 10% - note: This is not the correct answer.)
Retinoblastoma (Rb) is a malignant tumor of the eye that manifests in early childhood. Predisposition to retinoblastoma is an autosomal dominant trait with incomplete penetrance. For a certain form of low penetrance retinoblastoma, only 30% of children born with a mutated Rb allele develop eye tumors. If a heterozygous person carrying this mutation has children with a partner carrying two wild-type alleles, what is the probability that their first child will be affected by retinoblastoma? (Give the answer as a percentage including the % sign e.g. 10% - note: This is not the correct answer.)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Retinoblastoma (Rb) is a malignant tumor of the eye that manifests in early childhood.
Predisposition to retinoblastoma is an autosomal dominant trait with incomplete penetrance.
For a certain form of low penetrance retinoblastoma, only 30% of children born with a
mutated Rb allele develop eye tumors. If a heterozygous person carrying this mutation has
children with a partner carrying two wild-type alleles, what is the probability that their first
child will be affected by retinoblastoma?
(Give the answer as a percentage including the % sign e.g. 10% - note: This is not the correct
answer.)
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