The most common CF mutation is AF508; it accounts for approximate 70% of all mutant CFTR alleles worldwide. For a couple of northern European origin, what is their risk for having an affected child if each tests negative for AF508? If one tests positive and the other tests negative for AF508?

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter18: Genetics Of Behavior
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Problem 14QP: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known...
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The most common CF mutation is AF508; it accounts for approximately
70% of all mutant CFTR alleles worldwide. For a couple of northern
European origin, what is their risk for having an affected child if each
tests negative for AF508? If one tests positive and the other tests
negative for AF508?
Transcribed Image Text:The most common CF mutation is AF508; it accounts for approximately 70% of all mutant CFTR alleles worldwide. For a couple of northern European origin, what is their risk for having an affected child if each tests negative for AF508? If one tests positive and the other tests negative for AF508?
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