Type 1 albinism in humans is a rare hereditary condition associated with a reduced amount of active tyrosinase, an enzyme required for the conversion of the amino acid tyrosine to the dark pigment melanin. In the pedigree above, males are indicated by squares, females by circles and individuals with type 1 albinism are indicated by shading. Use A and a for the dominant (sufficient active tyrosinase) and recessive alleles (absent or insufficient tyrosinase activity), respectively. Remember that, when genotype is not known for a dominant phenotype, an m-dash is used (A– = AA or Aa). If individuals B and E marry, what is the probability that their first child will be affected by type 1 albinism? А. 1/2 В. 1/12 С. 1/4 D. 2/3 O E. 1/24

Q: X‑linked, recessive diseases, such as hemophilia, are extremely rare in the population. However,…

A: X-linked recessive disorders refers to the conditions where the defective gene that causes the…

Q: The following pedigree shows the inheritance of a human disorder. Affected individuals are shown…

A: A pedigree helps us to determine the inheritance of a trait across generations in a family.

Q: You have a Drosophila line that is homozygous for autosomal recessive alleles a, b, and c, linked…

A: The Recombinant Frequency tells us about the percentage of or the proportion of recombinants present…

Q: The allele for albinism is recessive to the allele for normal skin pigmentation. All individuals who…

A: An inherited disorder that presents with little or no melanin production, which results in either…

Q: In ogres, nose type results from a genetic maternal effect where the autosomal allele for a warty…

A: An autosomal allele is present on the chromosomes other than sex chromosomes.

Q: Polydactly is an autosomal dominant phenotype. In this pedigree, I-2 has one copy of the dominant…

A: Variable expressivity occurs due to the similar genetic condition among different people which…

Q: In man, muscular dystrophy is a condition in which the muscles waste away during early life and may…

A: Muscular dystrophy is a disease that involve a progressive loss of muscle mass and consequent loss…

Q: Many genetic disorders exhibit locus heterogeneity. Define andgive two examples of locus…

A: Locus heterogeneity is a phenomenon in which a particular disease is caused by mutations in…

Q: In the snail Cepaea nemoralis, an autosomal allele causing a banded shell (BB) is recessive to the…

A: Genetic linkage: - when genes are far apart or on the different chromosomes they are said to be…

Q: In goats, a beard is produced by an autosomal allele that is dominant in males and recessive in…

A: Phenotypic ratio- it is the relative number of offsprings offering manifestation of a particular…

Q: Lesch-Nyhan syndrome is due to a mutation in a gene that encodesa protein called…

A: Pedigree or family tree is a representation of an individual in a family or close relatives that…

Q: In the snail Cepaea nemoralis, an autosomal allele causing a banded shell (BB) is recessive to the…

A: Cepaea nemoralis is an air breathing species of land snail and also known as grove snail and brown…

Q: Pompe disease is a glycogen storage disorder caused by a lack of a-glucosidase, the enzyme that…

A: Alleles are the  alternative form of a gene that are located on the same locus of homologous…

Q: Ectrodactyly is a rare condition in which the fingers are absent and the hand is split. This…

A: Ectrodactyly is a genetic disorder which is usually inherited as an autosomal dominant trait. The…

Q: The pedigree shown below shows the inheritance of cystic fibrosis, a disorder that causes severe…

A: Cystic fibrosis is an inherited disorder that causes extreme damage to the lungs, digestive system,…

Q: There are two traits not shown in the pedigree: albinism (autosomal recessive) and Marfan syndrome…

A: A pedigree chart is a graphic that depicts the incidence and emergence of phenotypes of a certain…

Q: The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume…

A: Although the trait is skipped in the pedigree, autosomal recessive inheritance is discovered. The…

Q: Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family…

A: A pedigree chart is a diagram that shows the occurrence and appearance of phenotypes of a particular…

Q: Chands syndrome is an autosomal recessive condition characterized by very curly hair, underdeveloped…

A: A pedigree is a diagram of family relationships that uses symbols to represent people and lines to…

Q: In humans, cystic fibrosis and albinism are both inherited as independently assorting autosomal…

A: The law of independent assortment was first observed by Gregor Johann Mendel in 1865 during his…

Q: In pedigrees, individuals are usually specified by using a Roman numeral for their generation in the…

A: Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive…

Q: Tuberous Sclerosis (TS) is an autosomal dominant genetic disease characterized by seizures, mental…

A: Tuberous sclerosis is a rare autosomal dominant disease that causes non-cancerous tumors in various…

Q: ing pedigree. Solid symbols represent individuals affected by the trait. Assume complete penetrance…

A: a) To find: The mode of inheritance of the trait

Q: This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the…

A: Answer is given below.

Q: The attached image is a pedigree of a family with a history of sickle cell anemia (the individuals…

A: Sickle cell anemia is a genetic condition caused by a mutation in the gene that codes for…

Q: Define the pedigree symbol(s) associated with each of the following individuals. Please be as…

A: Pedigree: Pedigree is a family tree that is used to show the mode of inheritance of genetic traits/…

Q: In humans, a rare dominant disorder known as nail-patella syndromecauses abnormalities in the…

A: Pedigree analysis is a scientific approach that helps to study the inheritance of genes. In this…

Q: Below is a pedigree chart for a family that has a history of Alkaptonuria.   Individuals infected…

A: Pedigree analysis is a method to identify the inheritance of a genetic trait across generations.…

Q: Anhidrotic ectodermal dysplasia is an X-linked recessive disorder in humans characterized by small…

A: Anhidrotic ectodermal dysplasia (AED) is a type of immune deficiency observed in the human body. The…

Q: Kernel color in wheat is controlled by 2 pairs of genes (AABB). Determine the color of each…

A: The inheritance of kernel color in wheat is controlled by two genes. These are A and B genes.

Q: The pedigree below traces the inheritance of Albinism, a genetic disorder. Affected individuals,…

A: Introduction  Pedigree Analysis: this is the new approach to study the inheritance pattern in the…

Q: In humans the allele coding for normal metabolism of the amino acid phenylalanine (P) is dominant…

A: The alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: Ectrodactyly is a rare condition in which the fingers are absent and the hand is split. This…

A: A pedigree chart is a family tree that depicts the genetic representation of inheritance of a…

Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.