Duchenne muscular dystrophy is an inheritable disorder that results in muscle weakness, leading to walking and breathing difficulties and heart disease. Which of the following is a valid conclusion about the Duchenne muscular dystrophy pedigree shown above? a. Without further evidence, the genotypes of individuals II-2 and III-2 cannot be determined. b. Only individuals I-1 and II-3 are confirmed carriers of the Duchenne muscular dystrophy allele.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Duchenne muscular dystrophy is an inheritable disorder that results in muscle weakness, leading to walking and breathing difficulties and heart disease.

Which of the following is a valid conclusion about the Duchenne muscular dystrophy pedigree shown above?

a. Without further evidence, the genotypes of individuals II-2 and III-2 cannot be determined.
b. Only individuals I-1 and II-3 are confirmed carriers of the Duchenne muscular dystrophy allele.
2
II
1 2
3
4
II
1
2
4
Transcribed Image Text:2 II 1 2 3 4 II 1 2 4
Pedigree Conventions
Identical
twins
Male
Female
Non-identical
twins
Mating
Affected
individuals
Mating between
close relatives
Unaffected
individuals
Roman numerals
I
symbolize generations
Arabic numbers
symbolize individuals
within a given
generation
II
2 3
Birth order, within each
group of offspring, is
drawn left to right,
oldest to youngest
Transcribed Image Text:Pedigree Conventions Identical twins Male Female Non-identical twins Mating Affected individuals Mating between close relatives Unaffected individuals Roman numerals I symbolize generations Arabic numbers symbolize individuals within a given generation II 2 3 Birth order, within each group of offspring, is drawn left to right, oldest to youngest
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