The following pedigree shows the inheritance of a human disorder. Affected individuals areshown with filled symbols.IIIII2 35Based on the pedigree, propose the least likely inheritance pattern of the disease amongautosomal dominance, autosomal recessive, X-linked dominance and X-linked recessive.Your choice of answer can be impossible and possible. Explain your answer by giving theevidence that supports or opposes each mode of inheritance. You can reconstruct the tableshown below and draw the pedigree in your answer script. Write the possible genotype ofeach individual in the pedigree for each inheritance pattern proposed.Mode ofPossibilityExplanationsPedigreeinheritanceAutosomaldominanceAutosomalrecessiveX-linkeddominanceX-linkedrecessive

A pedigree helps us to determine the inheritance of a trait across generations in a family.

Answered: The following pedigree shows the…

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Biology

The following pedigree shows the inheritance of a human disorder. Affected individuals are shown with filled symbols.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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John and Sue are expecting a child, but are concerned about a rare autosomal recessive disease that is present in both of their families. In the pedigree, John is represented as individual III-11 and Sue is represented as individual III-12; both are unaffected. John's sister, III-10, and Sue's brother, III-13, both do not show evidence of the disease, but John's paternal grandmother and Sue's maternal grandfather both had the disease. Assign the appropriate symbol to each individual in the pedigree. I 3 4. Answer Bank II III 11 12 13 10 2.
If the mother is blood type AB , the father is Blood type O . Could the daughter who has type O be their child?
Cystic Fibrosis is an autosomal recessive disorder. A couple are both carriers of the recessive allele (both heterozygous (Cc)) and have the normal wild-type phenotype. What is the probability of the following occurring; If they have two children, what is the probability of them both being unaffected (CC or Cc) by the disease?
Four children have the following blood types: A, B, AB, and O. Could these children have the same two biological parents?
Given the pedigree below, answer the following questions. Note that filled symbols represent affected individuals. You assume that the allele carrying the disease is rare and therefore individuals marrying into the family are unlikely to have defective alleles. Also, assume complete penetrance. Q2) What are the genotypes of the following individuals listed in the table below? Use the uppercase “A” to represent the dominant allele and lowercase “a” for the recessive allele. Individual Genotype II-7 III-5 IV-1 IV-3 I-2 III-7
The following pedigree shows the inheritance of a rare genetic disorder. Determine the most likely mode of inheritance, and for exam practice (unmarked on the assignment) write a clear justification for your conclusion. Remember that some pedigrees don't provide sufficient data/information to discriminate between possibilities. If that is the case, select all the possible answers. I III Tb 2 3 1 1 3 autosomal dominant autosomal recessive Osex-linked dominant Osex-linked recessive O 2 H
The second pedigree involves albinism, an autosomal recessive trait. A couple has a son with normal pigmentation, a daughter with normal pigmentation, and an albino son. Another couple has three children, a son with normal pigmentation and two daughters with normal pigmentation. The daughter from the first couple marries the man from the second couple and they have three children together: an albino son, an albino daughter, and a daughter with normal pigmentation.Draw the pedigree on the next page
The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington’s disease. Using just the information on this pedigree, is Huntington’s disease caused by a dominant allele or recessive alleles? What are the genotypes of the grandparents (I-1 and I-2)? What are the genotypes of the parents (II-6 and II-7)? If the parents above have another child, what is the chance that they will be affected by the Hungtington’s disease allele? What are the genotypes of the unaffected children (III-8, 9, 10)? What is the chance that the unaffected children above will pass on a Huntington’s disease allele to their children? What is the genotype of the affected child (III-11)? What is the chance…
Below is a pedigree chart for a family that has a history of Alkaptonuria. Individuals infected with this condition can have darkened skin, brown urine, and can suffer from joint damage and other complications. Given this pedigree answer the following questions. Given the data in the pedigree chart is this genetic condition autosomal dominant or autosomal recessive? What are the genotypes for #1, #2, and #3? If either of the 4th generation "aa" females were to mate with a homozygous dominant male would any of their offspring illustrate the phenotype? Why or why not?
In a true breeding parental cross for an Autosomal recessive disease trait, the expected proportion of males in the F2 generation that are unaffected is:
Refer to the pedigree below for this question. Individuals who are shaded have an X-inked disorder. Those who are not shaded have the normal phenotype. Let "A" and "a" represent the dominant and recessive alleles, respectively. The disorder represented by the shaded symbol to the normal phenotype. Recessive Dominant A list of possible genotypes is given below. Derermine the appropriate genotype for each individual. Type in the number for the correct answer in the space provided. Do not type arything else in the space. It is ok to use an answer more than one time. 6. 1/2 x^ x^ + 1/2 x^ x 7. 1/4 X x^ +3/4 x^x 8. 3/4 X^ x^ + 1/4 x^ x 9. 1/3 x^ x^ + 2/3 x^ X" 10. 2/3 x^ x^ + 1/3 X^ x* 1. X^ Y 2. X Y 3. X^ xA 4. X^ X 5. X* х The genotype of individual I-1 is The genotype of individual II-5 is The genotype of individual I1-6 is The genotype of individual ill-6 is For the next question, give the probability as a fraction that is simplified to the lowest value. Type your fraction in # format…
Your brother has an autosomal recessive disorder, while you are unaffected. Neither one of your parents is affected. Explain how this is possible.