This pedigree depicts the inheritance of the mitochondrial disease Leber hereditary optic neuropathy (LHON). Individual I-1 does not show any symptoms of LHON, whereas her daughter and all three of her grandchildren are affected. Provide two explanations for this.

Q: X-linked ichthyosis is an X-linked recessive trait that manifests in part as dry, scaly skin…

A: If one allele is missing it is hemizygous. Heterozygous is the presence of two different alleles at…

Q: ake the example of B-thalassemia, an autosomal recessive genetic disease that particularly affects…

A: A point mutation is a change in the single nucleotide pair of DNA.

Q: Kate and her husband are both heterozygous for galactosemia gene. If Kate and her husband have four…

A: A group of hereditary disease known as galctosemia which means galactose in blood. Undigested…

Q: his pedigree shows the inheritance of sickle cell diseases. Please fill out the genotypes of the…

A: Answer: Sickle cell anemia is an autosomal recessive disorder which is transferred from parents to…

Q: Alpha thalassemia is a hereditary blood condition that results in varying levels of anemia. It is…

A: Hemoglobin is an oxygen carrier protein that is made of four chains, two alpha, and two beta chains.…

Q: Hemophilia is an X-linked disease associated with the inability to produce specific proteins in the…

A: Hemophilia is an X-linked disease associated with the inability to produce specific proteins in the…

Q: Thalassemia is an inherited anemic disorder in humans. Affected individuals exhibit either a minor…

A: BASIC INFORMATION  THALESSEMIA  it is a type of genetic disorder which originated in Mediterranean…

Q: Turner syndrome is a disease in which an individual is born with only a single X chromosome. Suppose…

A: Hemophilia is a bleeding condition that is commonly hereditary and affects the way one's blood…

Q: Using the pedigree, assume th

A: The pedigree chart is a diagram, which displays the appearance of the phenotypes of a particular…

Q: Neurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of…

A: The probability is 1/4

Q: Could the pedigree in Figure 2-31 be explained as an autosomal dominant disorder? Explain.

A: The genetic and phenotypic traits being passed from one generation to the other are called…

Q: This is a typical pedigree for a family that carries neurofibromatosis. Is individual I-2 most…

A: Pedigree analysis can help to determine genotypes, identify phenotypes, and predict how a trait will…

Q: The pedigree here shows the inheritance of a human disease knownas familial hypercholesterolemia.…

A: Pedigree analysis can be described as the record of a special genetical character or a disorder for…

Q: From this pedigree is it dominant or recessive. Is ur autosomal or sex-linked?

A: Pedigree is define a diagrammatic representation of the individuals of a family for a particular…

Q: Shown below is a pedigree for Phenylketonuria (PKU), an autosomal recessive metabolic disorder. The…

A: Phenylketonuria (PKU) is an autosomal recessive disorder.  Autosomal recessive trait…

Q: Chands syndrome is an autosomal recessive condition characterized by very curly hair, underdeveloped…

A: A pedigree is a diagram of family relationships that uses symbols to represent people and lines to…

Q: In humans, hemophilia is an X-linked recessive disorder that affects the gene for factor VIII…

A: Genetic disorders can be inherited either through recessive or dominant mutation. In case of a gene…

Q: Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family…

A: Pedigree analysis helps us to understand the mode of inheritance of a particular disease by…

Q: The pedigree below represents the inheritance of a rare genetic disorder (members joining the…

A: The answer is written in explanation box below:Explanation:…

Q: This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the…

A: Answer is given below.

Q: Muffy, a color blind female with blood type A (heterozygous to type O) is married to Biff, who is…

A: Given: Muffy, a color-blind female with blood type A (heterozygous to type O), married to Biff, who…

Q: Below is a pedigree chart for a family that has a history of Alkaptonuria.   Individuals infected…

A: Pedigree analysis is a method to identify the inheritance of a genetic trait across generations.…

Q: The pedigree below shows the recurrence of a rare neurological disease (large black symbols) and…

A: This information in the given pedigree can be solved by: There is a mutation in the progenitor cells…

Q: $HOT! a. If the disease were X-linked recessive, what would be the probability that a male child…

A: Ans : Before proceeding to the answer , we must understand basic terms . Like, monogenic disease…

Q: Achondroplasia is an autosomal dominant disorder characterized by disproportionate short stature:…

A: Achondroplasia is an autosomal dominant disorder, which leads to short-limb dwarfism in humans. It…

Q: Explain why it is possible for the proband in the following pedigree to have children of blood types…

A: A family may be a representation of our family tree. It appears how people inside a family are…

Q: Alberta is phenotypically normal, but her brother (Rodrigo) has albinism, which is caused by an…

A: Coordinated performance of the body organs, maintains optimum body functioning. The abnormal…

Q: The following pedigree illustrates the inheritance of Nance–Horan syndrome, a rare genetic condition…

A: The pedigree chart gives the inheritance pattern of a particular disease or trait over the…

Q: Filled (red) circles represent affected females. Filled (red) squares represent affected males.…

A: Pedigree is the analysis of a disease in the family history that gives us an idea about the…

Q: Jan and Michael are both carriers for the cystic fibrosis allele. If Jan and Michael have three…

A: Fraternal or dizygotic twins are produced when two different ova are fertilised by 2 different…

Q: The following pedigree describes the inheritance of Lesch-Nyhan syndrome, an X-linked recessive…

A: Lesch-Nyhan syndrome is a disorder that affects virtually entirely men. It is distinguished by…

Q: What is the Characteristic pedigree for mitochondrial disease?

A: The genes located on the nuclear chromosomes obey the Mendelian law of inheritance. In the human…

Q: A mother is heterozygous for the X-linked gene for colorblindness and also heterozygous for the…

A: Genes controls the genetic characteristics of an organism. The genes have two alleles that…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.