For decades scientists have been perplexed by different circumstances surrounding families with rare, early-onset auditory neuropathy (deafness). In some families, parents and grandparents of the proband have normal hearing, while in other families, a number of affected (deaf) family members are scattered throughout the pedigree, appearing in every generation. Assuming a genetic cause for each case, offer a reasonable explanation for the genetic origin of such deafness in the two types of families.

Q: As discussed in the text, almost 5% of Caucasians carry a recessive gene for cystic fibrosis. Until…

A: Cystic fibrosis is an inherited disease which is characterized by formation of thick, sticky mucus…

Q: Two unlinked genes, A and B, encode very similar enzymes involved in the production of purple flower…

A: In the given context, there are two independent genes, denoted as A and B, which are responsible for…

Q: Assuming that the trait represented by the filled symbols in the pedigree is an inherited trait due…

A: Answer - DOMINANT.

Q: Several members of the family in the pedigree who suffered from a disease are colored in black.…

A: Introduction :- A pedigree is a genetic representation of a family tree that shows how a trait or…

Q: The complete absence of one or more teeth (tooth agenesis) is a common trait in humans—indeed, more…

A: The pedigree chart indicates several generations and helps understand the inheritance pattern of a…

Q: In human beings, the gene for red‑green colorblindness (r) is sex‑linked and recessive to its allele…

A: normal vision male =XR Ycolor blind male= XrYnormal vision female= XR XRcolorblind female =Xr Xr…

Q: The pedigree below shows the inheritance of the rare blistering disease (epidermolysis) in dogs.…

A: Introduction A gene exists in two alternative forms called allele. If both the alleles of a gene is…

Q: Below is a pedigree from one family (two parents and eight children). Four of the children…

A: Pedigree chart It is a diagram that represents the occurrence of phenotypes of a particular gene in…

Q: hair, underdeveloped nails, and abnormally shaped eyelids. In the following pedigree, which…

A:

Q: ake the example of B-thalassemia, an autosomal recessive genetic disease that particularly affects…

A: A point mutation is a change in the single nucleotide pair of DNA.

Q: What is the probability that their firstborn child will be inartistic, immoral and greedy? What is…

A:

Q: a) In pedigree B What fraction of polydactylous female is in generation iii? b) for pedigree A,…

A: The pedigree indicates if the DNA is passed down unchanged from generation to generation. It can…

Q: In a family-based genetic study for a mental disorder called marijuana dependence, a total of 50…

A: Marijuana is widely used throughout the world. It is seen that about 50–70% of the liability to…

Q: Many genetic disorders exhibit locus heterogeneity. Define andgive two examples of locus…

A: Locus heterogeneity is a phenomenon in which a particular disease is caused by mutations in…

Q: The following family pedigree shows individuals afflicted with a metabolic disease. Suppose the male…

A: square represents male and the circle represents females.

Q: Lesch-Nyhan syndrome is due to a mutation in a gene that encodesa protein called…

A: Pedigree or family tree is a representation of an individual in a family or close relatives that…

Q: I || 1 1 2 2 O 3 1 2 4 3

A: Pedigree analysis is a tool that is used to study the inheritance pattern of a trait in a family or…

Q: In the results that Mendel obtained, the violet colored flower was dominant to the white flower…

A: According to Mendel, various hereditary traits are controlled by factors and there is a pair of…

Q: In the pedigree shown in Figure Q19–14, the first born in each of three generations is the only…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: The pedigree shown below shows the inheritance of cystic fibrosis, a disorder that causes severe…

A: Cystic fibrosis is an inherited disorder that causes extreme damage to the lungs, digestive system,…

Q: The following pedigree shows the inheritance of deafmutism.a. Provide an explanation for the…

A: Deafmutism is a term that is used to define a person who is deaf. These individuals use sign…

Q: cl II III IV 1 2 2 3 4 2 E) I II III IV S 3 D) I II HI IV 1 85 8 2

A: Introduction :  Pedigree charts are family trees that show the members of a family who have been…

Q: In pedigrees, individuals are usually specified by using a Roman numeral for their generation in the…

A: Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive…

Q: Without referring to the notation used to write the genotypes, how are you able to tell that a gene…

A: All these are defined by the Alleles they inherit and the type of phenotype they show  These can be…

Q: This pedigree (below) shows inheritance of a genetic disorder in a family. Assume the trait is rare.…

A: Gene is the segment of DNA responsible for heredity. Two or more alternative forms of genes…

Q: Below is a pedigree of a human genetic disease in which solid color indicates affected individuals.…

A: In the given pedigree, atleast one member in all generations have the disease. Therefore,…

Q: This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the…

A: Answer is given below.

Q: In the accompanying pedigree, the vertical lines stand for protan color blindness, and the…

A: Answer :  As seen in the inheritance pattern, both the conditions show presence only in males. This…

Q: The inheritance pattern of a rare form of Xeroderma pigmentosum is exhibited in the pedigree shown…

A: a. Because of the autosomal recessive inheritance pattern, this pedigree is autosomal recessive.  1.…

Q: A) Determine the type of inheritance shown on this pedigree. Explain your answer. B) Based on your…

A: Ans - Considering Genotype detention as D - for not having disease allele and d- for having…

Q: The complete absence of one or more teeth (tooth agenesis) is a common trait in humans—indeed, more…

A: Pedigree charts are diagrams that show the phenotypes and/or genotypes for a particular organism and…

Q: For the pedigrees below, name the inheritance pattern of the depicted disorder: If more than one…

A: Introduction :  A pedigree chart is a diagrammatic flow chart designed to display a person's genetic…

Q: Compare and contrast the molecular and phenotypic features of Prader-Willi and Angelman syndromes.

A: Prader villi and angle man syndrome are  imprinting disorders. Both are related to  abnormalities in…

Q: Type 1 albinism in humans is a rare hereditary condition associated with a reduced amount of active…

A: In type I albinism, the amount of active tyrosinase enzyme is reduced. This enzyme plays an…

Q: In humans, discoloration of the teeth is controlled by the dentine sialophosphoprotein (DSPP) gene…

A: DSPP gene that is responsible for discoloration of the teeth is present on chromosome number 4.   I…

Q: Type 1 albinism in humans is a rare hereditary condition associated with a reduced amount of active…

A: Albinism is a genetic disorder characterized by reduced melanin production. The tyrosinase enzyme…

Q: Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for…

A: Given: Cystic fibrosis (CF) is an autosomal recessive trait. Normal allele =  F      CF mutant…

Q: Marfan syndrome is a rare inherited human disorder characterizedby unusually long limbs and digits…

A: Marfan syndrome is a genetic disorder of connective tissues. In this, the connective tissues present…

Q: A woman diagnosed with early-onset Alzheimer's due to a mutation of the APP genehas children with a…

A: Azheimer's disease (AD) is a neurodegenerative disorder characterized by progressive dementia and…

Q: Although in reality the inheritance of cleft chin (e.g., the deep chin dimple seen in Ben Aimeck) is…

A: A detailed explanation with the correct answer is discussed in step 2.

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.