The following family pedigree shows individuals afflicted with a metabolic disease. Suppose the male (b) and the female (c) have 2 girls and 2 boys, indicate directly on the pedigree the symbols for these children that would be most consistent with the mode of inheritance observations in the pedigree? II II a b d. e IV

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A:

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A: a) I-1, II-4. II-6

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