The accompanying pedigree shows the pattern of transmission of two rare human
pituitary dwarfism. Family members with cataract are
shown with a solid left half of the symbol; those with
pituitary dwarfism are indicated by a solid right halfa. What is the most likely mode of inheritance of each of
these phenotypes? Explain.
b. List the genotypes of all members in generation III as
far as possible.
c. If a hypothetical mating took place between IV-1 and
IV-5, what is the probability of the first child’s being a
dwarf with cataracts? A phenotypically normal child?
(Problem 48 is adapted from J. Kuspira and R. Bhambhani, Compendium of Problems in Genetics. Copyright
1994 by Wm. C. Brown.)(Picture added)
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