Marfan syndrome is a disease caused by a rare dominant allele of the fibrillin-1 gene. Fibrillin-1 is an important component of the extracellular matrix, and people with the disease-causing allele have abnormal connective tissue. An affected mother (Marta) and an unaffected father (Joe) have one unaffected daughter (Luisa - she does not exhibit any traits of the syndrome). If Luisa has a child with Nico (unaffected), what is the probability that her child will inherit Marfan syndrome? Select one: a. 50% b. 25% c. 100% d. 0% e. 75%

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter5: The Inheritance Of Complex Traits
Section: Chapter Questions
Problem 23QP: If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this...
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Marfan syndrome is a disease caused by a rare dominant allele of the fibrillin-1 gene. Fibrillin-1 is an important component of the extracellular matrix, and people with the disease-causing allele have abnormal connective tissue. An affected mother (Marta) and an unaffected father (Joe) have one unaffected daughter (Luisa - she does not exhibit any traits of the syndrome). If Luisa has a child with Nico (unaffected), what is the probability that her child will inherit Marfan syndrome?

Select one:
a. 50%
b. 25%
c. 100%
d. 0%
e. 75%
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