Answered: Sickle cell anemia is an inheritable…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body. Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree).

Let Hb^S be the allele for sickle cell anemia and let Hb^A be the allele for normal red blood cells.

Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1?

Select one:

I-2	I-4	II-1	III-1
Hb^A_	Hb^AHb^S	Hb^AHb^S	Hb^A_

I-2	I-4	II-1	III-1
Hb^A_	Hb^AHb^S	Hb^AHb^S	Hb^AHb^S

I-2	I-4	II-1	III-1
Hb^AHb^S	Hb^AHb^S	Hb^AHb^S	Hb^AHb^S

I-2	I-4	II-1	III-1
Hb^AHb^A	Hb^AHb^A	Hb^AHb^A	Hb^AHb^A

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