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In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I IV V 김마 7800 9 10 10 머 Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is (are) suggested by this pedigree and then answer questions 4-6 O a. It is expected that neither V.4 or V.5 would have the disease b. It is not possible to say what the disease status of V.4 or V.5 would be O c. It is expected that both V.4 and V.5 would have the disease O d. V.4 will not have the disease if his brother does not e. V.4 cannot have the disease as his mother is unaffected Question 6) Based on your deduced mode of inheritance and observations of the pedigree, which of the following statements about the most likely disease status of individuals V.4 and V.5 (not given in Fig. 1) is CORRECT?

In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I IV V 김마 7800 9 10 10 머 Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is (are) suggested by this pedigree and then answer questions 4-6 O a. It is expected that neither V.4 or V.5 would have the disease b. It is not possible to say what the disease status of V.4 or V.5 would be O c. It is expected that both V.4 and V.5 would have the disease O d. V.4 will not have the disease if his brother does not e. V.4 cannot have the disease as his mother is unaffected Question 6) Based on your deduced mode of inheritance and observations of the pedigree, which of the following statements about the most likely disease status of individuals V.4 and V.5 (not given in Fig. 1) is CORRECT?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected || IV V 5600 orize 077808 15 10 9 10 CHO વ Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is (are) suggested by this pedigree and then answer questions 4-6 Question 6) Based on your deduced mode of inheritance and observations of the pedigree, which of the following statements about the most likely disease status of individuals V.4 and V.5 (not given in Fig. 1) is CORRECT? O a. It is expected that neither V.4 or V.5 would have the disease O b. It is not possible to say what the disease status of V.4 or V.5 would be O c. It is expected that both V.4 and V.5 would have the disease O d. V.4 will not have the disease if his brother does not O e. V.4 cannot have the disease as his mother is unaffected
Transcribed Image Text:In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected || IV V 5600 orize 077808 15 10 9 10 CHO વ Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is (are) suggested by this pedigree and then answer questions 4-6 Question 6) Based on your deduced mode of inheritance and observations of the pedigree, which of the following statements about the most likely disease status of individuals V.4 and V.5 (not given in Fig. 1) is CORRECT? O a. It is expected that neither V.4 or V.5 would have the disease O b. It is not possible to say what the disease status of V.4 or V.5 would be O c. It is expected that both V.4 and V.5 would have the disease O d. V.4 will not have the disease if his brother does not O e. V.4 cannot have the disease as his mother is unaffected
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