In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I IV V o 6000 600 10d60 5ம் 00000 10 CHO 80 Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is fare) sunnested by this periores and then answer questions 4-6
In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I IV V o 6000 600 10d60 5ம் 00000 10 CHO 80 Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian inheritance is fare) sunnested by this periores and then answer questions 4-6
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:In this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below.
Key
Ø
Female: affected
Female: unaffected
I
||
IV
V
TOLO
5
DO
머
9
10
a. Any of these options is possible
b. III.5 but not V.3 would display the disease
O c.
V.3 but not III.5 would display the disease
O d. Neither III.5 nor V.3 would display the disease
Oe. Both III.3 and V.3 would display the disease
10
ન
Male: affected
Male: unaffected
Deceased
Disease status not given
Dizygotic twins
Monozygotic twins
Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by
diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased
by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual
does not display the disease phenotype. Carriers of the disease are not indicated. Information on disease status is not known for generation I and is omitted for
the individuals represented by a symbol with an asterisk. The person referred to in the opening paragraph above is V.1. Consider which pattern(s) of Mendelian
inheritance is (are) suggested by this pedigree and then answer questions 4-6
Question 5) The disease status of individuals III.5, V.3 is not given in Fig. 1. Considering the pedigree and your deduced mode of inheritance which of the
following would you expect
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