1. What are the most probable genotypes of individuals II-9 and II-10 2. If individuals II-1 and II-2 have another child, what is the probability that it will have the disease?
1. What are the most probable genotypes of individuals II-9 and II-10 2. If individuals II-1 and II-2 have another child, what is the probability that it will have the disease?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
The following pedigree shows the pattern of inheritance for an uncommon human disease. Filled symbols indicate individuals with the disease: open symbols indicate normal individuals. Using the symbols A and a, answer the following questions about this pedigree.
1. What are the most probable genotypes of individuals II-9 and II-10
2. If individuals II-1 and II-2 have another child, what is the probability that it will have
the disease?
![### Pedigree Analysis for Inheritance Patterns
#### Explanation of Diagram
The diagram is a pedigree chart that shows the inheritance pattern of a particular genetic trait across three generations. The chart uses the following conventions:
- Circles represent females, and squares represent males.
- Shaded symbols denote individuals affected by the genetic trait.
- Unshaded symbols denote individuals unaffected by the trait.
**Generations:**
- **I:** The first generation.
- **II:** The second generation, consisting of progeny from the first generation.
- **III:** The third generation, consisting of progeny from the second generation.
**Individuals:**
- Each individual in the pedigree is numbered for identification.
#### Questions and Responses
1. **What is the most probable mode of inheritance (dominant or recessive) for this trait?**
- **Answer:** [ ]
2. **What is the most probable genotype of individual I-1?**
- **Answer:** [ ]
3. **What is the most probable genotype of individual I-2?**
- **Answer:** [ ]
4. **What are the most probable genotypes of individuals II-9 and II-10?**
- **Answer:** [ ]
5. **If individuals II-1 and II-2 have another child, what is the probability that it will have the disease?**
- **Answer:** [ ] %
### Detailed Analysis
**Graph Descriptions:**
- **I Generation:** There are two individuals, where individual I-1 is affected, and individual I-2 is unaffected. They have five children in the second generation (II).
- **II Generation:** There are eleven individuals, with four affected (II-1, II-2, II-6, and II-9). The individuals II-2 and II-3 have two children in the third generation, one of whom (III-2) is affected.
- **III Generation:** There are seven individuals, and individuals III-2 and III-4 are affected.
Understanding the pattern of affected and unaffected individuals can help determine whether the trait is dominant or recessive. Analyze the distribution and relationships to infer the mode of inheritance and likely genotypes.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1896aee9-4e1b-4aca-9af3-0b7f8caac28e%2F1112bb3f-c159-43a9-818a-6fc0fd3d09c1%2Fzsfoxv_processed.png&w=3840&q=75)
Transcribed Image Text:### Pedigree Analysis for Inheritance Patterns
#### Explanation of Diagram
The diagram is a pedigree chart that shows the inheritance pattern of a particular genetic trait across three generations. The chart uses the following conventions:
- Circles represent females, and squares represent males.
- Shaded symbols denote individuals affected by the genetic trait.
- Unshaded symbols denote individuals unaffected by the trait.
**Generations:**
- **I:** The first generation.
- **II:** The second generation, consisting of progeny from the first generation.
- **III:** The third generation, consisting of progeny from the second generation.
**Individuals:**
- Each individual in the pedigree is numbered for identification.
#### Questions and Responses
1. **What is the most probable mode of inheritance (dominant or recessive) for this trait?**
- **Answer:** [ ]
2. **What is the most probable genotype of individual I-1?**
- **Answer:** [ ]
3. **What is the most probable genotype of individual I-2?**
- **Answer:** [ ]
4. **What are the most probable genotypes of individuals II-9 and II-10?**
- **Answer:** [ ]
5. **If individuals II-1 and II-2 have another child, what is the probability that it will have the disease?**
- **Answer:** [ ] %
### Detailed Analysis
**Graph Descriptions:**
- **I Generation:** There are two individuals, where individual I-1 is affected, and individual I-2 is unaffected. They have five children in the second generation (II).
- **II Generation:** There are eleven individuals, with four affected (II-1, II-2, II-6, and II-9). The individuals II-2 and II-3 have two children in the third generation, one of whom (III-2) is affected.
- **III Generation:** There are seven individuals, and individuals III-2 and III-4 are affected.
Understanding the pattern of affected and unaffected individuals can help determine whether the trait is dominant or recessive. Analyze the distribution and relationships to infer the mode of inheritance and likely genotypes.
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