y 301Amelogenesis imperfecta is X-linked dominant. Affected XY individuals haveextremely thin enamel on the teeth while XX carriers have grooved teeth fromuneven deposition of enamel. If an unaffected XY individual were to producechildren with a XX carrier partner,a. what would be the expected chance of a XY child being affected with thedisease?b. what would be the expected chance of a XY child being affected with thedisease?

Answered: a. what would be the expected chance of…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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y 301
Amelogenesis imperfecta is X-linked dominant. Affected XY individuals have
extremely thin enamel on the teeth while XX carriers have grooved teeth from
uneven deposition of enamel. If an unaffected XY individual were to produce
children with a XX carrier partner,
a. what would be the expected chance of a XY child being affected with the
disease?
b. what would be the expected chance of a XY child being affected with the
disease?

Expert Solution

Step 1: Amelogenesis imperfecta

Amelogenesis imperfecta is a rare congenital disease, where the affected individual has a abnormal formation of enamel or the crown of the teeth. The tooth is thus small, discoloured or pitted leading to breakage. Mutations in AMELX, ENAM, MMP20 and FAM83H genes result in the disease, as these genes are vital for the formation of enamel.

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