The amino acid at the β82 position is in the central cavity that binds 2,3-bisphosphoglycerate in the deoxygenated form of hemoglobin. How would the mutation of Lys to Asn affect the ability to bind to 2,3-BPG? a. It would have no effect. b. It would have decreased 2,3-BPG binding. c. It would have increased 2,3-BPG binding. d. It would have increased 2,3-BPG binding at least two fold.
The amino acid at the β82 position is in the central cavity that binds 2,3-bisphosphoglycerate in the deoxygenated form of hemoglobin. How would the mutation of Lys to Asn affect the ability to bind to 2,3-BPG? a. It would have no effect. b. It would have decreased 2,3-BPG binding. c. It would have increased 2,3-BPG binding. d. It would have increased 2,3-BPG binding at least two fold.
Human Heredity: Principles and Issues (MindTap Course List)
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ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 20QP: If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it...
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The amino acid at the β82 position is in the central cavity that binds 2,3-bisphosphoglycerate in the deoxygenated form of hemoglobin. How would the mutation of Lys to Asn affect the ability to bind to 2,3-BPG?
a. It would have no effect.
b. It would have decreased 2,3-BPG binding.
c. It would have increased 2,3-BPG binding.
d. It would have increased 2,3-BPG binding at least two fold.
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