Suppose the biochemical pathway represented in Equation 5-10a is coupled at its first step to the hydrolysis of ATP to ADP. How would this change the expres- sion for AG of the pathway?

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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Suppose the biochemical pathway represented in Equation 5-10a is coupled at its
first step to the hydrolysis of ATP to ADP. How would this change the expres-
sion for AG of the pathway?
Transcribed Image Text:Suppose the biochemical pathway represented in Equation 5-10a is coupled at its first step to the hydrolysis of ATP to ADP. How would this change the expres- sion for AG of the pathway?
AG†
AG
AG
AS B*CD
(5-10a)
in which the AG*s give the standard free-energy change for each step. We
can write the free-energy change for each step:
[B]
А > В:
AGAB = AGÅB + RT 1n
[A]
[C]
AGBC = AGic + RT 1n
[B]
В — С:
(5-10b)
[D]
AGÉD + RT 1n
[C]
С — D:
AGCD =
Transcribed Image Text:AG† AG AG AS B*CD (5-10a) in which the AG*s give the standard free-energy change for each step. We can write the free-energy change for each step: [B] А > В: AGAB = AGÅB + RT 1n [A] [C] AGBC = AGic + RT 1n [B] В — С: (5-10b) [D] AGÉD + RT 1n [C] С — D: AGCD =
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