Propose structures for intermediates A and B in the scheme below. This three-step conversion is carried out by enzymes that require no redox cofactors (no FAD, NADH etc.) nor TPP. Which enzyme in the citric acid cycle has an activity most similar to enzyme 1? Which enzyme in the PPP or the citric acid cycle has an intermediate that bears similarity to intermediate B? H. OH COO™ Enzl A Enz2 B Enz3 OH

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Chapter1: Biochemistry: An Evolving Science
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Enzyme 1 is Aconitase and the starting material goes through both the hydration and dehydration mechanism.

I just need help with enzyme 2 and intermediate B, thank you

Propose structures for intermediates A and B in the scheme below. This three-step conversion is carried
out by enzymes that require no redox cofactors (no FAD, NADH etc.) nor TPP. Which enzyme in the citric acid
cycle has an activity most similar to enzyme 1? Which enzyme in the PPP or the citric acid cycle has an
intermediate that bears similarity to intermediate B?
H
OH
COO™
Enzl
A
Enz2
B
Enz3
OH
Transcribed Image Text:Propose structures for intermediates A and B in the scheme below. This three-step conversion is carried out by enzymes that require no redox cofactors (no FAD, NADH etc.) nor TPP. Which enzyme in the citric acid cycle has an activity most similar to enzyme 1? Which enzyme in the PPP or the citric acid cycle has an intermediate that bears similarity to intermediate B? H OH COO™ Enzl A Enz2 B Enz3 OH
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