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If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the carbonyl carbon atom (shown in red below), where would the label be found in glucose? Explain both in words and by using the pathway figure you have downloaded and printed to support your answer (or marked online).If you feel any of the positions will be partially labeled, indicate that clearly and explain

If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the carbonyl carbon atom (shown in red below), where would the label be found in glucose? Explain both in words and by using the pathway figure you have downloaded and printed to support your answer (or marked online).If you feel any of the positions will be partially labeled, indicate that clearly and explain

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the carbonyl carbon atom (shown in red below), where would the label be found in glucose? Explain both in words and by using the pathway figure you have downloaded and printed to support your answer (or marked online).If you feel any of the positions will be partially labeled, indicate that clearly and explain
The image depicts the structural formula of acetate with a carbon isotope label. The molecule consists of: - A methyl group, written as \( \text{H}_3\text{C}- \). - A carbon atom double-bonded to an oxygen atom, represented as \( \text{C} = \text{O} \). This carbon is labeled with the isotope \(^1\!\!3\text{C}\) in red, indicating the presence of carbon-13. - A carboxylate group, written as \( \text{COO}^- \), indicating the molecule has lost a proton and is negatively charged. The whole structure represents isotopically labeled acetate, which can be useful in tracking metabolic pathways or studying molecular mechanisms in scientific research.
Transcribed Image Text:The image depicts the structural formula of acetate with a carbon isotope label. The molecule consists of: - A methyl group, written as \( \text{H}_3\text{C}- \). - A carbon atom double-bonded to an oxygen atom, represented as \( \text{C} = \text{O} \). This carbon is labeled with the isotope \(^1\!\!3\text{C}\) in red, indicating the presence of carbon-13. - A carboxylate group, written as \( \text{COO}^- \), indicating the molecule has lost a proton and is negatively charged. The whole structure represents isotopically labeled acetate, which can be useful in tracking metabolic pathways or studying molecular mechanisms in scientific research.
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