Compare and contrast Pyruvate Dehydrogenase with a-ketoglutarate dehydrogenase Outline the mechanisms of both enzymes. Discuss the functions of the coenzymes. List the similarities and the differences between the 2 enzymes. Both are very large membrane bound complexes. What are the advantages of this strategy? Do a bit or research on the structure one of these enzymes. (include one recent reference) – How detailed is the enzyme structure known? What insight(s) does this structural detail give you about the enzyme mechanism.
Nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Nucleic Acids
Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
Compare and contrast Pyruvate Dehydrogenase with a-ketoglutarate dehydrogenase
Outline the mechanisms of both enzymes. Discuss the functions of the coenzymes. List the similarities and the
differences between the 2 enzymes. Both are very large membrane bound complexes. What are the advantages
of this strategy?
Do a bit or research on the structure one of these enzymes. (include one recent reference) – How detailed is the
enzyme structure known? What insight(s) does this structural detail give you about the enzyme mechanism.
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