A substrate-level phosphorylation is when a metabolite transfers a phosphate group to ADP to form ATP. Phosphorylation by ATP is the transfer of a phosphate from ATP to another metabolite. Consider the following reactions. In each a phosphate is hydrolyzed: Phosphoenolpyruvate + H2O = Pyruvate + Pi AG-61.9 kJ/mol 1,3-Bisphosphoglycerate + H2O = 3-Phosphoglycerate + Pi AG' = -49.3 kJ/mol = Phosphocreatine + H2O Creatine + Pi AG' -43 kJ/mol ATP + H2O ADP + Pi AG' = -30.5 kJ/mol Fructose 1,6-bisphosphate + H2O = Fructose 6-phosphate + Pi AG' Glucose 6-phosphate + H2O = Glucose + Pi Glycerol 3-phosphate + H2O = Glycerol + Pi AG' -13.8 kJ/mol = AG = -9.2 kJ/mol = -16.3 kJ/mol U Question 10 Under standard biochemical conditions, which of the following molecules can perform a substrate level phosphorylation in an exergonic reaction? (Select all that apply.) Phosphoenolpyruvate Phosphocreatine Fructose 1,6-bisphosphate Glucose 6-phosphate Glycerol 3-phosphate + H2O Glycerol + Pi Question 11 Under standard biochemical conditions, which of the following molecules can be phosphorylated by ATP in an exergonic reaction? (Select all that apply.) Pyruvate, yielding Phosphoenolpyruvate 3-Phosphoglycerate, yielding 1,3-bisphosphoglycerate Fructose 6-phosphate, yielding Fructose 1,6-bisphosphate Glucose, yielding Glucose 6-phosphate Glycerol, yielding Glycerol 3-phosphate 2 pts 2 pts

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Please answer questions 10 and 11 using the first picture for reference.

A substrate-level phosphorylation is when a metabolite transfers a phosphate group to ADP
to form ATP. Phosphorylation by ATP is the transfer of a phosphate from ATP to another
metabolite. Consider the following reactions. In each a phosphate is hydrolyzed:
Phosphoenolpyruvate + H2O = Pyruvate + Pi AG-61.9 kJ/mol
1,3-Bisphosphoglycerate + H2O = 3-Phosphoglycerate + Pi AG' = -49.3 kJ/mol
=
Phosphocreatine + H2O Creatine + Pi AG' -43 kJ/mol
ATP + H2O ADP + Pi
AG' = -30.5 kJ/mol
Fructose 1,6-bisphosphate + H2O = Fructose 6-phosphate + Pi AG'
Glucose 6-phosphate + H2O = Glucose + Pi
Glycerol 3-phosphate + H2O = Glycerol + Pi
AG' -13.8 kJ/mol
=
AG = -9.2 kJ/mol
= -16.3 kJ/mol
Transcribed Image Text:A substrate-level phosphorylation is when a metabolite transfers a phosphate group to ADP to form ATP. Phosphorylation by ATP is the transfer of a phosphate from ATP to another metabolite. Consider the following reactions. In each a phosphate is hydrolyzed: Phosphoenolpyruvate + H2O = Pyruvate + Pi AG-61.9 kJ/mol 1,3-Bisphosphoglycerate + H2O = 3-Phosphoglycerate + Pi AG' = -49.3 kJ/mol = Phosphocreatine + H2O Creatine + Pi AG' -43 kJ/mol ATP + H2O ADP + Pi AG' = -30.5 kJ/mol Fructose 1,6-bisphosphate + H2O = Fructose 6-phosphate + Pi AG' Glucose 6-phosphate + H2O = Glucose + Pi Glycerol 3-phosphate + H2O = Glycerol + Pi AG' -13.8 kJ/mol = AG = -9.2 kJ/mol = -16.3 kJ/mol
U
Question 10
Under standard biochemical conditions, which of the following molecules can perform a
substrate level phosphorylation in an exergonic reaction? (Select all that apply.)
Phosphoenolpyruvate
Phosphocreatine
Fructose 1,6-bisphosphate
Glucose 6-phosphate
Glycerol 3-phosphate + H2O Glycerol + Pi
Question 11
Under standard biochemical conditions, which of the following molecules can be
phosphorylated by ATP in an exergonic reaction? (Select all that apply.)
Pyruvate, yielding Phosphoenolpyruvate
3-Phosphoglycerate, yielding 1,3-bisphosphoglycerate
Fructose 6-phosphate, yielding Fructose 1,6-bisphosphate
Glucose, yielding Glucose 6-phosphate
Glycerol, yielding Glycerol 3-phosphate
2 pts
2 pts
Transcribed Image Text:U Question 10 Under standard biochemical conditions, which of the following molecules can perform a substrate level phosphorylation in an exergonic reaction? (Select all that apply.) Phosphoenolpyruvate Phosphocreatine Fructose 1,6-bisphosphate Glucose 6-phosphate Glycerol 3-phosphate + H2O Glycerol + Pi Question 11 Under standard biochemical conditions, which of the following molecules can be phosphorylated by ATP in an exergonic reaction? (Select all that apply.) Pyruvate, yielding Phosphoenolpyruvate 3-Phosphoglycerate, yielding 1,3-bisphosphoglycerate Fructose 6-phosphate, yielding Fructose 1,6-bisphosphate Glucose, yielding Glucose 6-phosphate Glycerol, yielding Glycerol 3-phosphate 2 pts 2 pts
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