V-class proton pumps run backward relative to the F-class ATP synthase. Consider the cartoon, which shows the conformations of the beta-subunits and ATPIADP + Pj of the F-class synthase. Which of the following associations between the conformation of the beta subunit and ATPIADP + P; is correct for V- Binding Change Mechanism loose binding ADP+P ATP ATP class pumps? C repeat ADP + P, ATP ATP ADP tight binding +P оpen ATP The open conformation releases ATP. Hydrolysis of ATP to ADP + Pi drives the change from tight to loose. Binding of ADP + Pj drives change from open to loose. O Hydrolysis of ATP to ADP + Pj drives the change from open to loose.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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V-class proton pumps run backward relative to the F-class ATP synthase. Consider the cartoon, which shows the conformations of the beta-subunits and
ATPIADP + Pj of the F-class synthase. Which of the following associations between the conformation of the beta subunit and ATP/ADP + P¡ is correct for V-
Binding Change Mechanism
loose
binding
ADP+P
ATP
ATP
class pumps?
C repeat
ADP
+ P,
ADP
АТР
tight
binding
АТР
+P
оpen
АТР
O The open conformation releases ATP.
Hydrolysis of ATP to ADP + P¡ drives the change from tight to loose.
O Binding of ADP + P¡ drives change from open to loose.
Hydrolysis of ATP to ADP + Pj drives the change from open to loose.
Transcribed Image Text:V-class proton pumps run backward relative to the F-class ATP synthase. Consider the cartoon, which shows the conformations of the beta-subunits and ATPIADP + Pj of the F-class synthase. Which of the following associations between the conformation of the beta subunit and ATP/ADP + P¡ is correct for V- Binding Change Mechanism loose binding ADP+P ATP ATP class pumps? C repeat ADP + P, ADP АТР tight binding АТР +P оpen АТР O The open conformation releases ATP. Hydrolysis of ATP to ADP + P¡ drives the change from tight to loose. O Binding of ADP + P¡ drives change from open to loose. Hydrolysis of ATP to ADP + Pj drives the change from open to loose.
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