For each Pi released, the typical free energy of hydrolysis of inorganic polyphosphate (polyP) is about 20 kJ/mol. In Worked Example 13–2, we determined that synthesizing ATP from ADP and Pi requires roughly 50 kJ/mol of energy in a cell. Is it possible for a cell to manufacture ATP from ADP using polyphosphate? Give an explanation for your response.
For each Pi released, the typical free energy of hydrolysis of inorganic polyphosphate (polyP) is about 20 kJ/mol. In Worked Example 13–2, we determined that synthesizing ATP from ADP and Pi requires roughly 50 kJ/mol of energy in a cell. Is it possible for a cell to manufacture ATP from ADP using polyphosphate? Give an explanation for your response.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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For each Pi released, the typical free energy of hydrolysis of inorganic polyphosphate (polyP) is about 20 kJ/mol. In Worked Example 13–2, we determined that synthesizing ATP from ADP and Pi requires roughly 50 kJ/mol of energy in a cell. Is it possible for a cell to manufacture ATP from ADP using polyphosphate? Give an explanation for your response.
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