Consider a uniport system where a carrier protein transports an uncharged substance A across a cell membrane. Suppose that at a certain ratio of [A]inside to [A]outside, the AG for the transport of substance A from outside the cell to the inside, Aoutside Ainside, is -11.3 kJ/mol at 25°C.
Consider a uniport system where a carrier protein transports an uncharged substance A across a cell membrane. Suppose that at a certain ratio of [A]inside to [A]outside, the AG for the transport of substance A from outside the cell to the inside, Aoutside Ainside, is -11.3 kJ/mol at 25°C.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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![**Unport System and Transport of Substance A**
Consider a uniport system where a carrier protein transports an uncharged substance A across a cell membrane. Suppose that at a certain ratio of \([A]_{inside}\) to \([A]_{outside}\), the \(\Delta G\) for the transport of substance A from outside the cell to the inside, \(A_{outside} \rightarrow A_{inside}\), is \(-11.3 \, \text{kJ/mol at 25°C}\).
**Key Question:**
What is the ratio of the concentration of substance A inside the cell to the concentration outside?
\[
\frac{[A]_{inside}}{[A]_{outside}} = \boxed{\phantom{answer}}
\]
**Select the True Statement:**
Choose the true statement about the transport of A under the conditions described.
- \( \bigcirc \) Increasing \([A]_{outside}\) will cause \(\Delta G\) for movement of \(A_{outside}\) to \(A_{inside}\) to become a smaller negative number.
- \( \bigcirc \) Decreasing the concentration of the uniport protein in the membrane will cause \(\Delta G\) to become a larger negative number.
- \( \bigcirc \) Movement of \(A_{outside}\) to \(A_{inside}\) will be spontaneous.
- \( \bigcirc \) Because \(\Delta G\) is negative, the ratio \([A]_{inside}/[A]_{outside}\) must be greater than one.
This educational content challenges you to understand the thermodynamics of membrane transport and to identify the conditions under which transport processes occur spontaneously.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F22e3fc62-a2ed-46b5-9f14-7888cf9520df%2F01e1551b-1676-47fb-9c34-8733dcf6bbfd%2Fexqvuu_processed.png&w=3840&q=75)
Transcribed Image Text:**Unport System and Transport of Substance A**
Consider a uniport system where a carrier protein transports an uncharged substance A across a cell membrane. Suppose that at a certain ratio of \([A]_{inside}\) to \([A]_{outside}\), the \(\Delta G\) for the transport of substance A from outside the cell to the inside, \(A_{outside} \rightarrow A_{inside}\), is \(-11.3 \, \text{kJ/mol at 25°C}\).
**Key Question:**
What is the ratio of the concentration of substance A inside the cell to the concentration outside?
\[
\frac{[A]_{inside}}{[A]_{outside}} = \boxed{\phantom{answer}}
\]
**Select the True Statement:**
Choose the true statement about the transport of A under the conditions described.
- \( \bigcirc \) Increasing \([A]_{outside}\) will cause \(\Delta G\) for movement of \(A_{outside}\) to \(A_{inside}\) to become a smaller negative number.
- \( \bigcirc \) Decreasing the concentration of the uniport protein in the membrane will cause \(\Delta G\) to become a larger negative number.
- \( \bigcirc \) Movement of \(A_{outside}\) to \(A_{inside}\) will be spontaneous.
- \( \bigcirc \) Because \(\Delta G\) is negative, the ratio \([A]_{inside}/[A]_{outside}\) must be greater than one.
This educational content challenges you to understand the thermodynamics of membrane transport and to identify the conditions under which transport processes occur spontaneously.
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