What is the Keq of Reaction #3? Show your work & clearly label your answer.Is Reaction #3 favorable under mammalian cellular conditions when the concentration of dGTP is 0.2 M, dCMP is 20 mM, dGMP-dCMP is 7 mM, and PPi is 10 mM? Use △G to support your answer. Reaction #1 - AG° = 7.3 kcal/molGUANINEOHdGMPReaction #3ofofofoReaction #2 - AG° = -12.2 kcal/molofofaOH+dGTPGUANINEOHdGTPGUANINECYTOSINEOHdCMPOHdCMPGUANINEOHdGMPCYTOSINE0=4-0GUANINECYTOSINEOHdGMP-dCMP+ ofofoPPiGUANINECYTOSINEOHdGMP-dCMPofofoPPi

In a general reaction such as: aA + bB ⇌ cC + dD At equilibrium (steady state), the concentration of…

What is the Keq of Reaction #3? Show your work & clearly label your answer. Is Reaction #3 favorable under mammalian cellular conditions when the concentration of dGTP is 0.2 M, dCMP is 20 mM, dGMP-dCMP is 7 mM, and PPi is 10 mM? Use △G to support your answer

What is the Keq of Reaction #3? Show your work & clearly label your answer. Is Reaction #3 favorable under mammalian cellular conditions when the concentration of dGTP is 0.2 M, dCMP is 20 mM, dGMP-dCMP is 7 mM, and PPi is 10 mM? Use △G to support your answer

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

What is the K_eq of Reaction #3? Show your work & clearly label your answer.

Is Reaction #3 favorable under mammalian cellular conditions when the concentration of dGTP is 0.2 M, dCMP is 20 mM, dGMP-dCMP is 7 mM, and PPi is 10 mM? Use △G to support your answer.

Reaction #1 - AG° = 7.3 kcal/mol
GUANINE
OH
dGMP
Reaction #3
ofofofo
Reaction #2 - AG° = -12.2 kcal/mol
ofofa
OH
+
dGTP
GUANINE
OH
dGTP
GUANINE
CYTOSINE
OH
dCMP
OH
dCMP
GUANINE
OH
dGMP
CYTOSINE
0=4-0
GUANINE
CYTOSINE
OH
dGMP-dCMP
+ ofofo
PPi
GUANINE
CYTOSINE
OH
dGMP-dCMP
ofofo
PPi

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