The table contains data about how different ASFV mutants affect enzyme activity-- for example the D29A mutant, where the D at position 29 was mutated to an A. Select three mutants at random, and for each mutant explain how that mutation could affect intermolecular force interactions (an example: hydrogen bonding
The table contains data about how different ASFV mutants affect enzyme activity-- for example the D29A mutant, where the D at position 29 was mutated to an A. Select three mutants at random, and for each mutant explain how that mutation could affect intermolecular force interactions (an example: hydrogen bonding
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The table contains data about how different ASFV mutants affect enzyme activity-- for example the D29A mutant, where the D at position 29 was mutated to an A. Select three mutants at random, and for each mutant explain how that mutation could affect intermolecular force interactions (an example: hydrogen bonding could be disrupted by this mutation because…
Transcribed Image Text:Kcat/Km
(M¯1 s-1)
Enzyme
Кт (иM)
Keat (s)
aDUTWT
ADUTD29A
aDUTR71A
aDUT$72A
aDUT$73A
ADUTL89A
aDUT190A
aDUTD91A
aDUTY94A
aDUTQ120A
ADUTA147
aDUTR149A
ADUTR149K
aDUTF154Y
SDUTWT
0.98 ± 0.2
4.37 + 0.15
4.46 × 106
4.62 × 10*
6.89 ± 0.2
0.31 ± 0.1
4.89 ± 0.35
4.16 ± 0.19
0.48 + 0.2
9.85 x 10*
1.34 x 106
0.54 × 10
1.58 x 106
5.58 + 0.3
5.44 ± 0.5
2.94 ± 0.7
0.47 + 0.26
0.75 + 0.2
16.76 ± 1.21
0.58 +0.4
3.51 x 10%
4.51 + 0.7
0.15 + 0.1
26.45 ± 0.2
0.58 ± 0.13
1.5 + 0.1
5.58 ± 0.6
0.33 x 105
0.56 x 105
9.60 × 106
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