Both caffeine (coffee, cola) and theophylline inhibit the enzyme phosphodiesterase that converts CAMP to AMP, allowing cAMP levels to temporarily remain high. Briefly discuss the possible effect of these drugs on the second messenger action of CAMP. What might the effect of caffeine of theophylline be on a signaling pathway?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Cyclic AMP (CAMP) is an important signaling molecule in cells. The
synthesis and degradation of CAMP is diagrammed in the following figure:
ATP
©2017 Pearson Education, Inc.
12pt
Adenylyl cyclase
Edit View Insert Format Tools Table
Paragraph
Pyrophosphate 3'c-
P-P₁
5'C
BI
Both caffeine (coffee, cola) and theophylline inhibit the enzyme
phosphodiesterase that converts CAMP to AMP, allowing cAMP levels to
temporarily remain high. Briefly discuss the possible effect of these drugs
on the second messenger action of CAMP. What might the effect of caffeine
of theophylline be on a signaling pathway?
CAMP
UA
Phosphodiesterase
T²
H₂O
AMP
⠀
Transcribed Image Text:Cyclic AMP (CAMP) is an important signaling molecule in cells. The synthesis and degradation of CAMP is diagrammed in the following figure: ATP ©2017 Pearson Education, Inc. 12pt Adenylyl cyclase Edit View Insert Format Tools Table Paragraph Pyrophosphate 3'c- P-P₁ 5'C BI Both caffeine (coffee, cola) and theophylline inhibit the enzyme phosphodiesterase that converts CAMP to AMP, allowing cAMP levels to temporarily remain high. Briefly discuss the possible effect of these drugs on the second messenger action of CAMP. What might the effect of caffeine of theophylline be on a signaling pathway? CAMP UA Phosphodiesterase T² H₂O AMP ⠀
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