Name a drug for treatment for overactive bladder syndrome which does not target the muscarinic M3 receptors directly, but rather targets one of the second messenger signalling molecules within the smooth muscle cells as a result of muscarinic M3 receptor activation.

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Q: BP HR 145/95 150 Isoproterenol 95/28 240 130/50

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Q: Which statement(s) is/are true regarding the release of glutamate? (Select all that apply)

A:

Q: You are studying a cell line that expresses both GPCR-A and G <-B, each receptc binds the same…

A: GPCR A increases cAMP and GPCR B decreases it. Hence any mutation affecting the GPCR B will be…

Q: A. What is the original ligand in the image? B. What is the second messenger in this pathway? C.…

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Q: Which of the following is the most important contributor to the difference between the resting…

A: The action potential is a sequence of variations in the voltage across the membrane. This action…

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Q: s a Na+/K+/2Cl- cotransporte

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A: The correct option is - vagal signals are transmitted via acetylcholine that binds alpha 7 nicotinic…

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Q: 1. Ionotropic GABA receptors are ligand-gated Cl channels which open during GABA-ergic signaling. a)…

A: Introduction Neurons are specialized cells that are the basic building blocks of the nervous system.…

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Q: In a hypothetical cAMP-mediated signal transduction cascade, the GTP-αs/adenylate cyclase…

A: cAMP is an intracellular secondary messenger for signal transduction which allows to pass the…

Q: cholerae, disrupt G Protein Coupled Receptor (GPCR) signaling pathways. They interfere with... the…

A: GPCR is a family of cell surface receptors that perform its action mainly through the action of GTP…

Q: In the introduction section the authors wrote “In general, the polarity-dependent mechanisms are…

A: Anodal stimulation is a type of electrical stimulation that involves passing a positive electric…

Q: Describe three ways in which a gradual increase inan extracellular signal can be sharpened by the…

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Q: Design a novel drug for treatment for overactive bladder syndrome which does not target the…

A: Introduction Overactive Bladder Syndrome or OAB is a medical condition in which the ability of the…

Q: The figure below shows the processes that occur during vision. Answer the following questions with…

A: Introduction: Membrane receptors are protein molecules that bind to or insert themselves into the…

Q: You are studying a drug that affects a cAMP signalling pathway that is normally initiated when a…

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A: The question asks which scenarios would lead to a decreased excitability of muscle cells due to the…

Q: 13) Draw a graph representing the changes in membrane potential across the axonal membrane before,…

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Q: In the discussion section the authors wrote “In this study, we observed that different paradigms of…

A: Transcranial electrical stimulation (tES) is a non-invasive brain stimulation technique that uses…

Q: When comparing two or more ligands, a larger numerical value for KD corresponds to a higher binding…

A: “Since you have asked multiple question, we will solve the first question for you. If youwant any…

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