1. Ionotropic GABA receptors are ligand-gated Cl channels which open during GABA-ergic signaling. a) Describe how under normal circumstances the opening of these channels leads to an IPSP. Do this in the context of Eci. b) Some cells in the body express a Na*/K+/2Cl cotransporter which pumps Cl into the ICF. Where these pumps are present, the same GABA receptor is actually excitatory. Again, in the context of Ea describe how the same receptor would be excitatory in cells which actively pump Clinto the ICF. You do not need to repeat information you provided in part (a)
1. Ionotropic GABA receptors are ligand-gated Cl channels which open during GABA-ergic signaling. a) Describe how under normal circumstances the opening of these channels leads to an IPSP. Do this in the context of Eci. b) Some cells in the body express a Na*/K+/2Cl cotransporter which pumps Cl into the ICF. Where these pumps are present, the same GABA receptor is actually excitatory. Again, in the context of Ea describe how the same receptor would be excitatory in cells which actively pump Clinto the ICF. You do not need to repeat information you provided in part (a)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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