Recent research has shown that activation of a topoisomerase enzyme leads to greater expression of some genes in neurons. These genes remain silent until topoisomerase is activated; they then are rapidly transcribed. Propose a mechanism for how topoisomerase might stimulate gene expression.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Recent research has shown that activation of a topoisomerase enzyme leads to greater expression of some genes in neurons.
These genes remain silent until topoisomerase is activated; they then
are rapidly transcribed. Propose a mechanism for how topoisomerase
might stimulate gene expression.
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