DNA methylation status is associated with transcriptional activity. First, describe the specific mechanism by which DNA methylation can control gene activation. Next, hypothesize what would happen to transcription in a cell that expressed an nonfunctional maintenance methyltransferase. Please give me long detailed answer.

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Sleep Physiology

Sleep is a condition of reduced muscle movement in the body. Awareness about the surroundings is reduced at the time of sleep. The body stays mildly responsive or non-responsive to external stimuli. The sleep-wake cycle is controlled by the circadian rhythm that produces a resting phase for the body.