GAL4 UASG 1 In the absence of galactose, GAL80 blocks GAL4 from GAL80 activating transcription. TATA Basal transcription apparatus GAL3 Galactose GAL4 TATA 3 GAL4 can now interact with basal transcription apparatus and stimulate transcription. GAL80 GAL3 2 When galactose is present, it binds to GAL3 and brings about a change in the conformation of GAL80. Galactose 17.7 Transcription is activated by GAL4 in response to galactose.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Examine Figure 17.7. What would be the effect on transcription if a mutation occurred in the gene that encodes GAL3, so that no functional GAL3 was produced?
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