Enhancers are sequences that affect the initiation of the transcription of genes that are hundreds or thousands of nucleotides away. Transcriptional activator proteins that bind to enhancers usually interact directly with transcription factors at promoters by causing the intervening DNA to loop out. An enhancer of bacteriophage T4 does not function by looping of the DNA (D. R. Herendeen et al. 1992. Science 256:1298–1303). Propose some mechanisms other than DNA looping by which this enhancer might affect transcription at a gene thousands of nucleotides away
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Enhancers are sequences that affect the initiation of the transcription
of genes that are hundreds or thousands of
Transcriptional activator proteins that bind to enhancers usually interact
directly with transcription factors at promoters by causing the
intervening DNA to loop out. An enhancer of bacteriophage T4 does not
function by looping of the DNA (D. R. Herendeen et al. 1992. Science
256:1298–1303). Propose some mechanisms other than DNA looping by
which this enhancer might affect transcription at a gene thousands of
nucleotides away
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
