Q1. After years of hard work, you have isolated a mutant of glucocorticoid receptor. Additional studies identified that the mutant is capable of binding to glucocorticoid hormone but defective in activating the transcription. Based of this information and your knowledge on glucocorticoid receptor signaling, how do you explain this phenomenon. List and explain all possible reasons for this defect in mutant.

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A: Note:- according to bartleby guidelines i will answered you only first three questions. Thank you.

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.