Which of the outcomes could potentially result if a mutation in the gene encoding the Ga subunit eliminates its GTPase activity? Choose three outcomes. Ga would be ineffective as a signal molecule (that is, it could not activate other proteins). The rate of GTP hydrolysis would increase. The concentration of CAMP in the cell would be continuously elevated. The cell would be unresponsive to molecules that act via CAMP. Go would be activated for an extended period. The signaling pathway could be activated for an extended period, possibly resulting in undesirable cell proliferation.
Which of the outcomes could potentially result if a mutation in the gene encoding the Ga subunit eliminates its GTPase activity? Choose three outcomes. Ga would be ineffective as a signal molecule (that is, it could not activate other proteins). The rate of GTP hydrolysis would increase. The concentration of CAMP in the cell would be continuously elevated. The cell would be unresponsive to molecules that act via CAMP. Go would be activated for an extended period. The signaling pathway could be activated for an extended period, possibly resulting in undesirable cell proliferation.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Which of the outcomes could potentially result if a mutation in the gene encoding the Go subunit eliminates its GTPase
activity? Choose three outcomes.
G& would be ineffective as a signal molecule (that is, it could not activate other proteins).
The rate of GTP hydrolysis would increase.
The concentration of cAMP in the cell would be continuously elevated.
The cell would be unresponsive to molecules that act via cAMP.
Go would be activated for an extended period.
The signaling pathway could be activated for an extended period, possibly resulting in undesirable cell proliferation.
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