G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are two basic receptor types by which cells transduce signals. Classify each statement as describing GPCRs, RTKs, both types of receptors, or neither. GPCRs ligand binding induces conformational change in receptor activate heterotrimeric G proteins directly an example is the insulin receptor RTKs Answer Bank autophosphorylation of receptor can initiate signal an example is the epinephrine receptor Both transports some ligands through the membrane phosphorylation of receptor can terminate signal or desensitize receptor structure contains seven transmembrane helices Neither receptor activation causes phosphorylation of its cytosolic subunits

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Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.