Puting a metabolic pathway map together which includes glycolysis, gluconeogenesis, glycogen synthesis & glycogenolysis, and the two types of fermentation, and pyruvate oxidation (to acetyl-CoA). The map should have/illustrate/show all of the indicated 6 pathways stated previously on the same page, to emphasize how these processes are related to each other. map should include: a) Clear labels for all the pathways b) All the pathways shown on the same page and correctly integrated with each other, i.e., it should be clear which reactions are shared by different pathways c) The names of all metabolites (common abbreviations may be used)
Electron Transport Chain
The electron transport chain, also known as the electron transport system, is a group of proteins that transfer electrons through a membrane within mitochondria to create a gradient of protons that drives adenosine triphosphate (ATP)synthesis. The cell uses ATP as an energy source for metabolic processes and cellular functions. ETC involves series of reactions that convert redox energy from NADH (nicotinamide adenine dinucleotide (NAD) + hydrogen (H)) and FADH2(flavin adenine dinucleotide (FAD)) oxidation into proton-motive force(PMF), which is then used to synthesize ATP through conformational changes in the ATP synthase complex, a process known as oxidative phosphorylation.
Metabolism
Picture a campfire. It keeps the body warm on a cold night and provides light. To ensure that the fire keeps burning, fuel needs to be added(pieces of wood in this case). When a small piece is added, the fire burns bright for a bit and then dies down unless more wood is added. But, if too many pieces are placed at a time, the fire escalates and burns for a longer time, without actually burning away all the pieces that have been added. Many of them, especially the larger chunks or damp pieces, remain unburnt.
Cellular Respiration
Cellular respiration is the cellular process involved in the generation of adenosine triphosphate (ATP) molecules from the organic nutritional source obtained from the diet. It is a universal process observed in all types of life forms. The glucose (chemical formula C6H12O6) molecules are the preferred raw material for cell respiration as it possesses a simple structure and is highly efficient in nature.
Puting a
map should include:
a) Clear labels for all the pathways
b) All the pathways shown on the same page and correctly integrated with each other, i.e., it should be clear which reactions are shared by different pathways
c) The names of all metabolites (common abbreviations may be used)
d) The names of all enzymes
e) All relevant cofactors/co-substrates discussed in class, clearly showing, where ATP is used and produced
f) Double or single arrows representing reversible or irreversible reactions, respectively
g) All "high-energy" intermediates clearly labeled with an asterisk (*)
h) Labels for cellular locations of the pathways/reactions
I) also include mitochondrial matrix,
j) gluconeogenesis energy moelcues (ATP, GTP,NADH), '
k) lactate transported out of the cell in lactate production and
L) cori cycle (lactate being exported from cell)
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