Please explain the significance of the metabolites that served as inhibitors (CTP) or activators (ATP) in the context of the biosynthetic pathway presented in Figure 1 HCO3 + Glutamine + ATPCarbamoyl phosphate + AspartateAT CaseFigure 1: Pyrimidine synthetic pathway.N-carbamoylaspartateUMPUTPCTP

Pyrimidines are nitrogenous bases found in nucleic acids. Pyrimidines are heterocyclic organic…

Answered: Please explain the significance of the…

Please explain the significance of the metabolites that served as inhibitors (CTP) or activators (ATP) in the context of the biosynthetic pathway presented in Figure 1

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

Please explain the significance of the metabolites that served as inhibitors (CTP) or activators (ATP) in the context of the biosynthetic pathway presented in Figure 1

HCO3 + Glutamine + ATP
Carbamoyl phosphate + Aspartate
AT Case
Figure 1: Pyrimidine synthetic pathway.
N-carbamoylaspartate
UMP
UTP
CTP

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Step 1: ATCase and Pyrimidine biosynthesis

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