Name some HMG CoA reductase inhibitors? Please answer at your own words.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Name some HMG CoA reductase inhibitors? Please answer at your own words.
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HMG-CoA Reductase (3-hydroxy-3-methyl-glutaryl-CoA) is the rate-limiting enzyme of the cholesterol and other isoprenoid biosynthesis pathways. It is a transmembrane protein located in the smooth endoplasmic reticulum.
HMG-CoA reductase inhibitors inhibit the activity of HMG-CoA reductase that catalyzes the reduction of HMG-CoA to mevalonate. HMG-CoA reductase inhibitors help in the treatment of hypercholesterolemia.
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