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The synthesis öf phosphoenolpyruvate from pyruvate proceeds through two enzyme-catalyzed reactions. These reactions:

The synthesis öf phosphoenolpyruvate from pyruvate proceeds through two enzyme-catalyzed reactions. These reactions:

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**The synthesis of phosphoenolpyruvate from pyruvate proceeds through two enzyme-catalyzed reactions. These reactions:** - O Are allosterically regulated by fructose-1,6-bisphosphate - O Are both irreversible because they are coupled to nucleotide hydrolysis - O Lead to the net production of ATP - O Are energetically costly: pyruvate carboxylase consumes ATP, and phosphoenolpyruvate carboxykinase consumes GTP
Transcribed Image Text:**The synthesis of phosphoenolpyruvate from pyruvate proceeds through two enzyme-catalyzed reactions. These reactions:** - O Are allosterically regulated by fructose-1,6-bisphosphate - O Are both irreversible because they are coupled to nucleotide hydrolysis - O Lead to the net production of ATP - O Are energetically costly: pyruvate carboxylase consumes ATP, and phosphoenolpyruvate carboxykinase consumes GTP
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