One important role of Fas and Fas ligand is to mediate the elimination of tumor cells by killer lymphocytes. In a study of 35 primary lung and colon tumors, half the tumors were found to have amplified and overexpressed a gene for a secreted protein that binds to Fas ligand. How do you suppose that overexpression of this protein might contribute to the survival of these tumor cells? Explain your reasoning.

Q: 1) One cell-signaling pathway implicated in the regulation of cell division is the mTOR/Akt pathway.…

A: mTOR/Akt pathway involved in cell division.

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Q: Platelet-derived growth factor (PDGF) is, as its name suggests, stored in and secreted by platelets.…

A: PDGF is naturally synthesized and stored by the body. Its primary role is to encourage the growth…

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A: Metabolic syndrome is a group of disorders that occur in tandem and increase your risk of heart…

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Q: Given the following scenario, indicate if this will ‘promote’ or ‘prevent’ cancer development: An…

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Q: 14)How does a compound that inhibits the GTPase activity of ras affect cell responses to growth…

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A: Chronic lymphocytic leukaemia is a malignancy in which the bone marrow produces an excessive number…

Q: Cells require growth factors from other cells to proliferate   B. Growth Factors must enter cell…

A: Growth factor signalling is a cell signalling pathway that regulates the growth and development of…

Q: Explain the overexpression of a protein that binds to the Fas ligand contributes to the survival of…

A: A  transmembrane protein called Fas ligand is found on the surface of lymphocyte cells. It binds to…

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A: Ataxia-telangiectasia ( A-T) is caused by mutations in the ATM (ATM serine/threonine kinase or…

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A: According to the question, a graph has been displayed which demonstrates that T cell Receptor…

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Q: One important role of Fas and Fas ligand is to medi-ate the elimination of tumor cells by killer…

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A:

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A: Most receptors dimerize during their association with their ligands. This dimerization provides them…

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Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.