Mutations in bacterial promoters may increase or decrease the rate of gene transcription. Promoter mutations that increase transcription are termed up-promoter mutations, and those that decrease transcription are termed down-promoter mutations. The sequence of the −10 site of the promoter for the lac operon is TATGTT (see Figure 14.5). Would you expect each of the following mutations to be an up- promoter or down-promoter mutation? A. TATGTT to TATATT B. TATGTT to TTTGTT C. TATGTT to TATGAT
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Mutations in bacterial promoters may increase or decrease the
rate of gene transcription. Promoter mutations that increase
transcription are termed up-promoter mutations, and those that
decrease transcription are termed down-promoter mutations.
The sequence of the −10 site of the promoter for the lac operon
is TATGTT (see Figure 14.5). Would you expect each of the
following mutations to be an up-
promoter or down-promoter
mutation?
A. TATGTT to TATATT
B. TATGTT to TTTGTT
C. TATGTT to TATGAT
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